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TRADD Antibody

TRADD Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameTRADD Primary Polyclonal Antibody
Also known asTRADD PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenTRADD
SpecificityThis is a highly specific antibody against TRADD
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range120-170/310
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from mouse of mouse TRADD
Gene ID number71609
Swiss ProtQ3U0V2
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Overexpression of TRADD leads to two major TNF-induced responses, The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, apoptosis and activation of NF-kappa-B (By similarity), leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A, Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 9130005N23Rik, TNFR1-associated DEATH domain protein, TNFRSF1A-associated via death domain, Tradd, Tumor necrosis factor receptor type 1-associated DEATH domain protein, AA930854
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetTRADD
Short nameTRADD Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameTNFRSF1A-associated via death domain (Antibody to)
Alternative techniqueantibodies
Alternative to gene target Hs, TRADD and IDBG-36010 and ENSG00000102871 and 8717, TRADD and IDBG-633302 and ENSBTAG00000012642 and 504707, Tradd and IDBG-186918 and ENSMUSG00000031887 and 71609, binding, bridging, bridging and also this GO :0070513: death domain binding, bridging and molecular function this GO :0070513 and death domain binding and molecular function this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097191 and extrinsic apoptotic signaling pathway and biological process this GO :2001239 and regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, nuclei, this GO :0004871 and signal transducer activity and molecular function this GO :0005164 and tumor necrosis factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0008625 and extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :0019900 and kinase binding and molecular function this GO :0031264 and death-inducing signaling complex and cellular component this GO :0032403 and protein complex binding and molecular function this GO :0033209 and tumor necrosis factor-mediated signaling pathway and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043234 and protein complex and cellular component this GO :0043235 and receptor complex and cellular component this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051291 and protein heterooli this GO merization and biological process this GO :0051798 and positive regulation of hair follicle development and biological process this GO :0060090 and binding, this GO :0004871: signal transducer activity, this GO :0004871: signal transducer activity and also this GO :0005164: tumor necrosis factor receptor binding and also this GO :0005515: protein binding and also this GO :0019900: kinase binding and also this GO :0032403: protein complex binding and also this GO :0042802: identical protein binding and also this GO :0060090: binding, this GO :0005164: tumor necrosis factor receptor binding, this GO :0005515: protein binding, this GO :0019900: kinase binding, this GO :0032403: protein complex binding, this GO :0042802: identical protein binding, this GO :0060090: binding, this GO :0070513: death domain binding, 89862, TNFRSF1A-associated via death domain
Identity 12030
Gene TRADD
Long gene name TNFRSF1A associated via death domain
Synonyms gene name TNFRSF1A-associated via death domain
Synonyms Hs, 89862
Locus 16q22, 1
Discovery year 1999-05-07
GenBank acession L41690
Entrez gene record 8717
Pubmed identfication 7758105 22333735
Havana BLAST/BLAT OTTHUMG00000137519

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