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TRAF3 Antibody, ALEXA FLUOR 488

TRAF3 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, TRAF3 Polyclonal Antibody
Also known asAnti-TRAF3 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTRAF3
SpecificityThis is a highly specific antibody against TRAF3
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range130-180/568
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TRAF3
Gene ID Number7187
Swiss ProtQ13114
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Down-regulates proteolytic processing of NFKB2, Inhibits TRAF2-mediated activation of NF-kappa-B, Inhibits activation of NF-kappa-B in response to LTBR stimulation, Is an essential constituent of several E3 ubiquitin-protein ligase complexes, May have E3 ubiquitin-protein ligase activity and promote 'Lys-63'-linked ubiquitination of target proteins, Part of signaling pathways leading to the production of cytokines and interferon, Plays a role T-cell dependent immune responses, Plays a role in the regulation of antiviral responses, Promotes ubiquitination and proteasomal degradation of MAP3K14, Required for normal antibody isotype switching from IgM to IgG, and plays a central role in the regulation of B-cell survival, and thereby inhibits non-canonical activation of NF-kappa-B, Regulates pathways leading to the activation of NF-kappa-B and MAP kinases
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms CAP-1 CD40bp CRAF1 LAP1
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the TRAF3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetTRAF3
Short nameTRAF3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, tumor necrosis factor receptor-associated factor 3 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target CAP-1 and CAP1 and CD40bp and CRAF1 and IIAE5 and LAP1, Plasma membranes, TRAF3 and IDBG-21240 and ENSG00000131323 and 7187, TRAF3 and IDBG-635183 and ENSBTAG00000013475 and 506182, Traf3 and IDBG-172558 and ENSMUSG00000021277 and 22031, thioesterase binding, this GO :0001817 and regulation of cytokine production and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005164 and tumor necrosis factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005739 and mitochondrion and cellular component this GO :0005768 and endosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0008063 and Toll signaling pathway and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0009898 and cytoplasmic side of plasma membrane and cellular component this GO :0016567 and protein ubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0030162 and regulation of proteolysis and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0031996 and thioesterase binding and molecular function this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032480 and negative regulation of type I interferon production and biological process this GO :0032648 and regulation of interferon-beta production and biological process this GO :0033209 and tumor necrosis factor-mediated signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0035631 and CD40 receptor complex and cellular component this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0050688 and regulation of defense response to virus and biological process, this GO :0004842: ubiquitin-protein transferase activity, this GO :0004842: ubiquitin-protein transferase activity and also this GO :0004871: signal transducer activity and also this GO :0005164: tumor necrosis factor receptor binding and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0016874: ligase activity and also this GO :0019901: protein kinase binding and also this GO :0031625: ubiquitin protein ligase binding and also this GO :0031996: thioesterase binding, this GO :0004871: signal transducer activity, this GO :0005164: tumor necrosis factor receptor binding, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0016874: ligase activity, this GO :0019901: protein kinase binding, this GO :0031625: ubiquitin protein ligase binding, this GO :0031996: thioesterase binding, TNF receptor-associated factor 3
Identity 12033
Gene TRAF3
Long gene name TNF receptor associated factor 3
Locus 14q32, 32
Discovery year 1998-05-05
GenBank acession U21092
Entrez gene record 7187
Pubmed identfication 7530216 7859281
RefSeq identity NM_145725
Classification Zinc fingers TNF receptor associated factors
Havana BLAST/BLAT OTTHUMG00000171902
Locus Specific Databases LRG_229

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