Name : Transferrin Receptor 2 Antibody
Supplier : NJS POLY
Price :389
SKU : GEN2748581978
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | Transferrin Receptor 2 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus) |
| Tested applications | WB |
| Recommended dilutions | 5-1ug/ml, Western blot: 0 |
| Notes | Titration of the Transferrin Receptor 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use | This Transferrin Receptor 2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q9JKX3 |
| Purity | Antigen affinity |
| Description | As a consequence, By radiation hybrid analysis, Fleming et al, However, Kawabata et al, Nonetheless, TFRC expression in liver is undetectable in hereditary hemochromatosis patients with hepatic iron loading, The majority of hepatic iron uptake under normal circumstances is transferrin-mediated, This gene is a member of the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease associated(PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain, as in other nonreticuloendothelial cell types, expression of TFRC in hepatocytes, hepatic iron loading in hemochromatosis patients is progressive, is downregulated in response to increased intracellular iron, (1999) mapped the TFR2 gene to chromosome 7q22, (2000) provided support for a mechanism that involves the uptake of transferrinbound iron by TFR2, Transferrin receptor protein 2 is a protein that in humans is encoded by the TFR2 gene |
| Immunogen | An amino acid sequence from the N-terminus of mouse TFR2 (MEQRWGLLRRVQQWS) was used as the immunogen for this Transferrin Receptor 2 antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Transferrin Receptor 2 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | Transferrin Receptor 2 |
| Short name | Transferrin Receptor 2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Transferrin Receptor 2 (Antibody to) |
| Alternative technique | antibodies |