TRBP (46D1) Monoclonal Antibody

TRBP (46D1) Monoclonal Antibody size: 0.1ml 362

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 362

Size 0.1ml

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Long name	TRBP (46D1) Monoclonal Antibody
Also known as	TRBP (46D1) Monoclonal Antibody
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	TRBP
Specificity	This is a highly specific antibody against TRBP
Modification(s)	None
Modification site(s)	Unmodified antibody
Clonality	Monoclonal
Clone number	46D1
Concentration	1ug per 1ul
Source	Recombinant human protein purified from E, coli(GST-TRBP)
Gene ID number	6895
Swiss Prot	Q15633
Tested Applications	WB
Recommended dilutions	5 ug/mL), WB (0
Cross reactivity	Mouse, Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	AGO2 and TARBP2, AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2, Binds to the HIV-1 TAR RNA which is located in the long terminal repeat (LTR) of HIV-1, Component of the RISC loading complex (RLC), DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2, May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1, May also promote translation of TAR-containing RNAs independently of EIF2AK2/PKR, This is achieved in part at least by binding to and inhibiting EIF2AK2/PKR, Within the RLC/miRLC, also known as the micro-RNA (miRNA) loading complex (miRLC), and stimulates translation of TAR-containing RNAs, thereby reducing phosphorylation and inhibition of EIF2S1/eIF-2-alpha, which is composed of DICER1, Required for formation of the RNA induced silencing complex (RISC)
Purification method	Purified by Protein G
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	RISC-loading complex subunit TARBP2, TAR RNA-binding protein 2, TARBP2, TRBP, TRBP1, TRBP2, Trans-activation-responsive RNA-binding protein, LOQS
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About	Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target	TRBP (46D1) Monoclonal
Short name	TRBP (46D1) Monoclonal Antibody
Technique	Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name	TRBP (46D1) monoclonal (Antibody to)
Alternative technique	antibodies
Identity	11570
Gene	TARBP2P1
Long gene name	RISC loading complex RNA binding subunit pseudogene 1 , TARBP2P1
Synonyms gene	TARBP2P
Synonyms gene name	Tar (HIV-1) RNA binding protein 2 pseudogene TAR (HIV-1) RNA binding protein 2 pseudogene 1
Synonyms	TRBP
Locus	8q22, 3
Discovery year	1994-04-12
GenBank acession	AF197477
Entrez gene record	6896
Pubmed identfication	2011739
RefSeq identity	NG_001199

TRBP (46D1) Monoclonal Antibody

TRBP (46D1) Monoclonal Antibody size: 0.1ml 362

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