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TRIM28 Antibody / KAP1

TRIM28 Antibody / KAP1 size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenTRIM28 / KAP1
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0
NotesOptimal dilution of the TRIM28 antibody should be determined by the researcher
Intented useThis TRIM28 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q13263
PurityAntigen affinity
Description DNA damage repair, Its functionality is dependent upon post-translational modifications, KAP1 is a ubiquitously expressed protein involved in many critical functions including: transcriptional regulation, Phosphorylation of KAP1 acts as a deactivator of the protein in many of its mechanisms while sumoylation acts as an activator, The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors, The protein localizes to the nucleus and is thought to associate with specific chromatin regions, also known as transcriptional intermediary factor 1b (TIF1b) and KAP1 (KRAB-associated protein-1), and apoptosis, cellular differentiation and proliferation, is a protein that in humans is encoded by the TRIM28 gene, viral suppression, Tripartite motif-containing 28
ImmunogenAmino acids 699-835 of human TRIM28 were used as the immunogen for the TRIM28 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the TRIM28 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
LocalizationNuclear
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetTRIM28 / KAP1
Short nameTRIM28 Antibody / KAP1
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameTRIM28 (Antibody to) / KAP1
Alternative techniqueantibodies
Identity 16384
Gene TRIM28
Long gene name tripartite motif containing 28
Synonyms gene name tripartite motif-containing 28
Synonyms TIF1B KAP1 TF1B RNF96 PPP1R157
Synonyms name protein phosphatase 1, regulatory subunit 157
Locus 19q13, 4
Discovery year 2001-08-10
Entrez gene record 10155
Pubmed identfication 11331580 11226167
RefSeq identity NM_005762
Classification Tripartite motif containing PHD finger proteins Ring finger proteins Protein phosphatase 1 regulatory subunits
Havana BLAST/BLAT OTTHUMG00000183546

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