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TRIM32/BBS11 Antibody, Biotin Conjugated

TRIM32/BBS11 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, TRIM32/BBS11 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTRIM32/BBS11
SpecificityThis is a highly specific antibody against TRIM32/BBS11
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from mouse TRIM32
Gene ID number22954
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Additionally, Mutations in the TRIM32 gene cause two forms of autosomal recessive muscular dystrophy designated limb girdle muscular dystrophy type 2H (LGMD2H) and sarcotubular myopathy (STM), TRIM32, TRIM32 has six C-terminal NHL domains, TRIM32 mutations can also result in Bardet-Biedl syndrome (BBS), The TRIM32 gene encodes an E3 ubiquitin ligase, UbcH5c and UbcH6, a RING-finger and a coiled-coil motif, a protein that attaches ubiquitin to a lysine residue on a target protein and acts in conjunction with ubiquitin-conjugating enzymes UbcH5a, an autosomal recessive disorder characterized by pigmentary retinopathy, contains a domain structure composed of a B-box, hypogenitalism, it is expressed mainly in the skeletal muscle, learning disabilities and obesity, like all TRIM proteins, polydactyly, renal abnormalities, Tripartite motif-containing protein 32 (TRIM32) belongs to the tripartite motif (TRIM) protein family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms HT2A TATIP BBS11
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetTRIM32/BBS11 Conjugated
Short name Conjugated, TRIM32/BBS11 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, TRIM32/BBS11 (Antibody to)
Alternative techniqueantibodies
Identity 16380
Gene TRIM32
Long gene name tripartite motif containing 32
Synonyms gene LGMD2H
Synonyms gene name limb girdle muscular dystrophy 2H (autosomal recessive) tripartite motif-containing 32
Locus 9q33, 1
Discovery year 2001-08-10
GenBank acession U18543
Entrez gene record 22954
Pubmed identfication 11331580 7778269 16606853
RefSeq identity NM_012210
Classification Tripartite motif containing Ring finger proteins Bardet-Biedl syndrome associated
Havana BLAST/BLAT OTTHUMG00000021026
Locus Specific Databases Leiden Muscular Dystrophy Pages Leiden Muscular Dystrophy pages LRG_211

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