Filters

TRIO Antibody / Triple functional domain protein

TRIO Antibody / Triple functional domain protein size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenTRIO / Triple functional domain protein
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions1-0, 5ug/ml, Western blot: 0
NotesOptimal dilution of the TRIO antibody should be determined by the researcher
Intented useThis TRIO antibodyis to be used only for research purposes and not for diagnostics
Uniprot #O75962
PurityAntigen affinity
Description Additionally, These domains suggest that this enzyme may play a key role in several signaling pathways that control cell proliferation, This gene encodes a large protein that functions as a GDP to GTP exchange factor, This protein promotes the reorganization of the actin cytoskeleton, respectively, specific for Rac1 and RhoA, the TRIO protein contains 3 functional domains: a serine/threonine kinase domain and 2 guanine nucleotide exchange factor (GEF) domains for the family of Rho-like GTPases, thereby playing a role in cell migration and growth, Triple functional domain protein is a protein that in humans is encoded by the TRIO gene
ImmunogenAmino acids QLRIFERDAIDIISDLESWNDELSQQMNDFDTEDLTIAEQRLQH of human TRIO were used as the immunogen for the TRIO antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the TRIO antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
LocalizationCytoplasmic
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetTRIO / Triple functional domain protein
Short nameTRIO Antibody / Triple functional domain protein
Technique antibodies against human proteins, antibodies for, functional
Alternative nametrio Rho guanine nucleotide exchange factor (Antibody to) / Triple functional domain protein
Alternative techniqueantibodies
Alternative to gene target ARHGEF23 and tgat, Plasma membranes, TRIO and IDBG-12835 and ENSG00000038382 and 7204, TRIO and IDBG-631218 and ENSBTAG00000005514 and 538292, Trio and IDBG-131599 and ENSMUSG00000022263 and 223435, alcohol group as acceptor, alcohol group as acceptor and also this GO :0019899: enzyme binding, alcohol group as acceptor and molecular function this GO :0019899 and enzyme binding and molecular function this GO :0032321 and positive regulation of Rho GTPase activity and biological process this GO :0035023 and regulation of Rho protein signal transduction and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0051056 and regulation of small GTPase mediated signal transduction and biological process this GO :0097190 and apoptotic signaling pathway and biological process, this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005089 and Rho guanyl-nucleotide exchange factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007185 and transmembrane receptor protein tyrosine phosphatase signaling pathway and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0007411 and axon guidance and biological process this GO :0009103 and lipopolysaccharide biosynthetic process and biological process this GO :0016020 and membrane and cellular component this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005085: guanyl-nucleotide exchange factor activity and also this GO :0005089: Rho guanyl-nucleotide exchange factor activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005085: guanyl-nucleotide exchange factor activity, this GO :0005089: Rho guanyl-nucleotide exchange factor activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0016773: phosphotransferase activity, this GO :0019899: enzyme binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0016773: phosphotransferase activity, transferring phosphorus-containing groups and molecular function this GO :0016773 and phosphotransferase activity, trio Rho guanine nucleotide exchange factor
Identity 12303
Gene TRIO
Long gene name trio Rho guanine nucleotide exchange factor
Synonyms gene name triple functional domain (PTPRF interacting)
Synonyms ARHGEF23
Locus 5p15, 2
Discovery year 1997-01-29
GenBank acession AF091395
Entrez gene record 7204
Pubmed identfication 8643598
RefSeq identity NM_007118
Classification Rho guanine nucleotide exchange factors I-set domain containing
Havana BLAST/BLAT OTTHUMG00000131057

Similar products

Subscribe to our Newsletter