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Trk B Antibody, ALEXA FLUOR 488

Trk B Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, Trk B Polyclonal Antibody
Also known asAnti-TrkB PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTrkB
SpecificityThis is a highly specific antibody against TrkB
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range30-80/822
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Trk B
Gene ID Number4915
Swiss ProtQ16620
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Alternatively can also bind NTF3/neurotrophin-3 which is less efficient in activating the receptor but regulates neuron survival through NTRK2, FRS2, FRS2, Hence, May also play a role in neutrophin-dependent calcium signaling in glial cells and mediate communication between neurons and glia, PLCG1 also leads to NF-Kappa-B activation and the transcription of genes involved in cell survival, Receptor for BDNF/brain-derived neurotrophic factor and NTF4/neurotrophin-4, Recruits, SH2B1, SH2B1, SH2B2 activates the GRB2-Ras-MAPK cascade that regulates for instance neuronal differentiation including neurite outgrowth, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades, Thereby, Through PLCG1 and the downstream protein kinase C-regulated pathways controls synaptic plasticity, Through SHC1, Through the same effectors controls the Ras-PI3 kinase-AKT1 signaling cascade that mainly regulates growth and survival, Upon ligand-binding, and synapse formation and plasticity, autophosphorylation and activation, differentiation, it is able to suppress anoikis, migration, phosphorylates and/or activates several downstream effectors including SHC1, plays a role in learning and memory by regulating both short term synaptic function and long-term potentiation, proliferation, the apoptosis resulting from loss of cell-matrix interactions, undergoes homodimerization, Receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms BDNF/NT-3 growth factors receptor, GP145-TrkB, NTRK2, Neurotrophic tyrosine kinase receptor type 2, TrkB tyrosine kinase, Tropomyosin-related kinase B, trk-B, TRKB
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Trk B Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetTrk B
Short nameTrk B Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, Trk B (Antibody to)
Alternative techniqueantibodies

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