| Alternative name1 | NGFR, NTR), Nerve Growth Factor Receptor, Neurotrophin Receptor, phosphorylated (Tyr490) (Tyrosine Kinase Receptor A, Anti-TrkA |
| Alternative name2 | NGFR, NTR), Nerve Growth Factor Receptor, Neurotrophin Receptor, phosphorylated (Tyr490) (Tyrosine Kinase Receptor A, TrkA |
| Alternative name3 | NGFR, NTR), Nerve Growth Factor Receptor, Neurotrophin Receptor, phosphorylated (Tyr490) (Tyrosine Kinase Receptor A, TrkA |
| Alternative name4 | TrkA |
| Alternative name5 | NGFR, NTR), Nerve Growth Factor Receptor, Neurotrophin Receptor, phosphorylated (Tyr490) (Tyrosine Kinase Receptor A, Anti -TrkA |
| Other names | High affinity nerve growth factor receptor, Neurotrophic tyrosine kinase receptor type 1, OTTHUMP00000038736, OTTHUMP00000234666, OTTHUMP00000234667, OTTHUMP00000234668, OTTHUMP00000234669, Oncogene TRK, TRK1-transforming tyrosine kinase protein, TRK1-transforming tyrosine kinase protein, high affinity nerve growth factor receptor, neurotrophic tyrosine kinase, p140-TrkA, receptor, type 1, tyrosine kinase receptor A, TRKA |
| Gene name | N/A |
| Gene name synonims | N/A |
| Other gene names | DKFZp781I14186, MTC, NTRK1, TRK, TRK, TRK1, TRKA, Trk-A, p140-TrkA, NTRK1 |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | IgG |
| Clone | Polyclonal antibody |
| Host organism | Source: Human, Host: Rabbit |
| Species reactivity | Mouse, Rat, Human |
| Specificity and cross-reactivity | Can also detect the corresponding residues of phosphorylated TrkB and TrkC, Species sequence homology: human, mouse, Recognizes endogenous levels of rat Trk only when phosphorylated at Tyr490 |
| Purification method | Affinity Purified by Protein A affinity chromatography |
| Form/Appearance | 0, 150mM sodium chloride, 50% glycerol, No preservative added, pH 7, 1mg/ml BSA, 5, Supplied as liquid in 10mM HEPES |
| Concentration | N/A |
| Storage and shipping | Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage, For maximum recovery of product, For optimal long term storage, Further dilutions can be made in assay buffer, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for: | Immunoprecipitation (IP), Western Blot (WB), ELISA (EL/EIA) |
| Description | Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target | NGFR, NTR), Nerve Growth Factor Receptor, Neurotrophin Receptor, phosphorylated (Tyr490) (Tyrosine Kinase Receptor A, TrkA |
| Short name | NGFR, NTR), Nerve Growth Factor Receptor, Neurotrophin Receptor, phosphorylated (Tyr490) (Tyrosine Kinase Receptor A, TrkA |
| Alternative name | NTR), Nerve Growth Factor Receptor, Neurotrophin Receptor, nerve growth factor receptor, phosphorylated (Tyr490) (Tyrosine phosphorylation catalyst Receptor A, TrkA |
| Alternative to gene target | CD271 and Gp80-LNGFR and p75(NTR) and p75NTR and TNFRSF16, NGFR and IDBG-57653 and ENSG00000064300 and 4804, NGFR and IDBG-638806 and ENSBTAG00000020979 and 353110, Ngfr and IDBG-209608 and ENSMUSG00000000120 and 18053, nerve growth factor binding, nuclei, this GO :0004871 and signal transducer activity and molecular function this GO :0004872 and receptor activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005035 and death receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005768 and endosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006886 and intracellular protein transport and biological process this GO :0007165 and signal transduction and biological process this GO :0007411 and axon guidance and biological process this GO :0007417 and central nervous system development and biological process this GO :0009986 and cell surface and cellular component this GO :0010468 and regulation of gene expression and biological process this GO :0012501 and programmed cell death and biological process this GO :0016048 and detection of temperature stimulus and biological process this GO :0017137 and Rab GTPase binding and molecular function this GO :0021675 and nerve development and biological process this GO :0031069 and hair follicle morphogenesis and biological process this GO :0031293 and membrane protein intracellular domain proteolysis and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032922 and circadian regulation of gene expression and biological process this GO :0040037 and negative regulation of fibroblast growth factor receptor signaling pathway and biological process this GO :0042488 and positive regulation of odontogenesis of dentin-containing tooth and biological process this GO :0042593 and glucose homeostasis and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043281 and regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043588 and skin development and biological process this GO :0045786 and negative regulation of cell cycle and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048146 and positive regulation of fibroblast proliferation and biological process this GO :0048406 and nerve growth factor binding and molecular function this GO :0050770 and regulation of axonogenesis and biological process this GO :0050771 and negative regulation of axonogenesis and biological process this GO :0050772 and positive regulation of axonogenesis and biological process this GO :0051799 and negative regulation of hair follicle development and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097481 and neuronal postsynaptic density and cellular component this GO :2001235 and positive regulation of apoptotic signaling pathway and biological process this GO :2001273 and regulation of glucose import in response to insulin stimulus and biological process, this GO :0004871: signal transducer activity, this GO :0004871: signal transducer activity and also this GO :0004872: receptor activity and also this GO :0004888: transmembrane signaling receptor activity and also this GO :0005035: death receptor activity and also this GO :0005515: protein binding and also this GO :0017137: Rab GTPase binding and also this GO :0031625: ubiquitin protein ligase binding and also this GO :0048406: nerve growth factor binding, this GO :0004872: receptor activity, this GO :0004888: transmembrane signaling receptor activity, this GO :0005035: death receptor activity, this GO :0005515: protein binding, this GO :0017137: Rab GTPase binding, this GO :0031625: ubiquitin protein ligase binding, this GO :0048406: nerve growth factor binding, nerve growth factor receptor |
| Identity | 7809 |
| Gene | NGFR |
| Long gene name | nerve growth factor receptor |
| Synonyms gene name | member 16) , nerve growth factor receptor (TNFR superfamily |
| Synonyms | TNFRSF16 CD271 p75NTR |
| Synonyms name | low affinity nerve growth factor receptor TNFR superfamily, member 16 |
| Locus | 17q21, 33 |
| Discovery year | 2001-06-22 |
| GenBank acession | M14764 |
| Entrez gene record | 4804 |
| Pubmed identfication | 3022937 3006050 |
| Classification | CD molecules Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT | OTTHUMG00000161495 |
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