Name : TRP12 Antibody, ALEXA FLUOR 350
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN6234704419
| Long name | ALEXA FLUOR 350 Conjugated, TRP12 Polyclonal Antibody |
| Also known as | Anti-TRP12 PAb ALEXA FLUOR 350 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 350, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | TRP12 |
| Specificity | This is a highly specific antibody against TRP12 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 310-360/871 |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TRPV4 |
| Gene ID Number | 59341 |
| Swiss Prot | Q9HBA0 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification, Acts as a regulator of intracellular Ca(2+) in synoviocytes, Also activated by low pH, Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism, Increase of intracellular Ca(2+) potentiates currents, Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12, Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers, citrate and phorbol esters, 13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8, Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 343nm/442nm |
| Synonyms | OTRPC4 TRP12 VROAC VRL-2 VR-OAC CMT2C |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 350, Alexa Fluor |
| Gene target | TRP12 |
| Short name | TRP12 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 350 |
| Alternative name | ALEXA FLUOR 350, TRP12 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 18083 |
| Gene | TRPV4 |
| Long gene name | transient receptor potential cation channel subfamily V member 4 |
| Synonyms gene name | member 4 , subfamily V, transient receptor potential cation channel |
| Synonyms name | osmosensitive transient receptor potential channel 4 |
| Locus | 12q24, 11 |
| Discovery year | 2002-01-29 |
| GenBank acession | AF263523 |
| Entrez gene record | 59341 |
| Pubmed identfication | 11025659 11081638 16382100 20037587 |
| RefSeq identity | NM_021625 |
| Classification | Ankyrin repeat domain containing Transient receptor potential cation channels |
| Havana BLAST/BLAT | OTTHUMG00000169277 |
| Locus Specific Databases | LRG_372 |