Filters

TRP12 Antibody, ALEXA FLUOR 350

TRP12 Antibody, ALEXA FLUOR 350 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 350 Conjugated, TRP12 Polyclonal Antibody
Also known asAnti-TRP12 PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTRP12
SpecificityThis is a highly specific antibody against TRP12
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range310-360/871
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TRPV4
Gene ID Number59341
Swiss ProtQ9HBA0
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification, Acts as a regulator of intracellular Ca(2+) in synoviocytes, Also activated by low pH, Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism, Increase of intracellular Ca(2+) potentiates currents, Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12, Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers, citrate and phorbol esters, 13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8, Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Synonyms OTRPC4 TRP12 VROAC VRL-2 VR-OAC CMT2C
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetTRP12
Short nameTRP12 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, TRP12 (Antibody to)
Alternative techniqueantibodies
Identity 18083
Gene TRPV4
Long gene name transient receptor potential cation channel subfamily V member 4
Synonyms gene name member 4 , subfamily V, transient receptor potential cation channel
Synonyms name osmosensitive transient receptor potential channel 4
Locus 12q24, 11
Discovery year 2002-01-29
GenBank acession AF263523
Entrez gene record 59341
Pubmed identfication 11025659 11081638 16382100 20037587
RefSeq identity NM_021625
Classification Ankyrin repeat domain containing Transient receptor potential cation channels
Havana BLAST/BLAT OTTHUMG00000169277
Locus Specific Databases LRG_372

Subscribe to our Newsletter