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TRPM4 Antibody

TRPM4 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameTRPM4 Primary Polyclonal Antibody
Also known asTRPM4 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenTRPM4
SpecificityThis is a highly specific antibody against TRPM4
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range800-850/1214
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TRPM4
Gene ID number54795
Swiss ProtQ8TD43
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Affects T-helper 1 (Th1) and T-helper 2 (Th2) cell motility and cytokine production through differential regulation of calcium signaling and NFATC1 localization, Controls insulin secretion in pancreatic beta-cells, Cs(+) >, Enhances cell proliferation through up-regulation of the beta-catenin signaling pathway, Involved in myogenic constriction of cerebral arteries, It thereby plays a central role in cadiomyocytes, K(+) >, Li(+)), May also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca(2+) overload, Mediates transport of monovalent cations (Na(+) >, Participates in T-cell activation by modulating Ca(2+) oscillations after T lymphocyte activation, While it is activated by increase in intracellular Ca(2+), cochlea hair cells etc, dorsal root and vomeronasal neurons, endocrine pancreas cells, it is impermeable to it, kidney epithelial cells, leading to depolarize the membrane, neurons from entorhinal cortex, which is required for NFAT-dependent IL2 production, Calcium-activated non selective (CAN) cation channel that mediates membrane depolarization
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Calcium-activated non-selective cation channel 1, LTrpC-4, LTrpC4, Long transient receptor potential channel 4, Melastatin-4, TRPM4, TRPM4B, Transient receptor potential cation channel subfamily M member 4, hTRPM4, PFHB1B
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetTRPM4
Short nameTRPM4 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name member 4 (Antibody to), subfamily M, transient receptor potential cation channel
Alternative techniqueantibodies
Alternative to gene target ATP binding, Plasma membranes, TRPM4 and IDBG-62419 and ENSG00000130529 and 54795, TRPM4 and IDBG-640445 and ENSBTAG00000006139 and 100295930, Trpm4 and IDBG-182463 and ENSMUSG00000038260 and 68667, member 4, subfamily M, this GO :0002407 and dendritic cell chemotaxis and biological process this GO :0002724 and regulation of T cell cytokine production and biological process this GO :0005216 and ion channel activity and molecular function this GO :0005227 and calcium activated cation channel activity and molecular function this GO :0005262 and calcium channel activity and molecular function this GO :0005516 and calmodulin binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006811 and ion transport and biological process this GO :0006816 and calcium ion transport and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016925 and protein sumoylation and biological process this GO :0034220 and ion transmembrane transport and biological process this GO :0055085 and transmembrane transport and biological process this GO :0070588 and calcium ion transmembrane transport and biological process this GO :0090263 and positive regulation of canonical Wnt signaling pathway and biological process, this GO :0005216: ion channel activity, this GO :0005216: ion channel activity and also this GO :0005227: calcium activated cation channel activity and also this GO :0005262: calcium channel activity and also this GO :0005516: calmodulin binding and also this GO :0005524: ATP binding, this GO :0005227: calcium activated cation channel activity, this GO :0005262: calcium channel activity, this GO :0005516: calmodulin binding, this GO :0005524: ATP binding, transient receptor potential cation channel
Identity 17993
Gene TRPM4
Long gene name transient receptor potential cation channel subfamily M member 4
Synonyms gene name member 4 , subfamily M, transient receptor potential cation channel
Synonyms FLJ20041
Locus 19q13, 3
Discovery year 2002-01-11
GenBank acession AK000048
Entrez gene record 54795
Pubmed identfication 11535825 16382100
RefSeq identity NM_017636
Classification Transient receptor potential cation channels
Havana BLAST/BLAT OTTHUMG00000183184

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