Name : TRPM8 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN5261463427
| Long name | Biotin Conjugated, TRPM8 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | TRPM8 |
| Specificity | This is a highly specific antibody against TRPM8 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human TRPM8 |
| Gene ID number | 79054 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Activated by icilin, Activated upon depolarization, Involved in menthol sensation, Permeable for monovalent cations sodium, Temperature sensing is tightly linked to voltage-dependent gating, Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing, The chemical agonists menthol functions as a gating modifier, and cesium and divalent cation calcium, by being activated by cold temperature below 25 degrees Celsius, changes in temperature resulting in graded shifts of its voltage-dependent activation curves, cold and modulation of intracellular pH, eucalyptol, menthol, potassium, shifting activation curves towards physiological membrane potentials, Receptor-activated non-selective cation channel involved in detection of sensations such as coolness |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | TRPM8 Conjugated |
| Short name | Conjugated, TRPM8 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, TRPM8 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 17961 |
| Gene | TRPM8 |
| Long gene name | transient receptor potential cation channel subfamily M member 8 |
| Synonyms gene name | member 8 , subfamily M, transient receptor potential cation channel |
| Locus | 2q37, 1 |
| Discovery year | 2002-01-11 |
| GenBank acession | AC005538 |
| Entrez gene record | 79054 |
| Pubmed identfication | 16382100 |
| RefSeq identity | NM_024080 |
| Classification | Transient receptor potential cation channels |
| Havana BLAST/BLAT | OTTHUMG00000059129 |