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TRPV6 Antibody

TRPV6 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenTRPV6
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the TRPV6 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis TRPV6 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q9H1D0
PurityAntigen affinity
Description Heteromeric assembly with TRPV5 seems to modify channel properties, In vitro, Inactivation includes both, TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating (By similarity), The channel is activated by low internal calcium level, a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin- dependent mechanism, and the current exhibits an inward rectification, including Ca(2+) reabsorption in intestine, is slowly inhibited by Mg(2+) in a voltage-independent manner, probably including intracellular calcium store depletion, the latter may be regulated by phosphorylation, Calcium selective cation channel probably involved in Ca(2+) uptake in various tissues
ImmunogenThis TRPV6 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 352-385 amino acids from the Central region of human TRPV6
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the TRPV6 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetTRPV6
Short nameTRPV6 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name member 6 (Antibody to), subfamily V, transient receptor potential cation channel
Alternative techniqueantibodies
Alternative to gene target Plasma membranes, TRPV6 and IDBG-45160 and ENSG00000165125 and 55503, TRPV6 and IDBG-636798 and ENSBTAG00000024219 and 614878, Trpv6 and IDBG-140883 and ENSMUSG00000029868 and 64177, calmodulin binding, member 6, subfamily V, this GO :0005216 and ion channel activity and molecular function this GO :0005262 and calcium channel activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005516 and calmodulin binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006811 and ion transport and biological process this GO :0006816 and calcium ion transport and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0017158 and regulation of calcium ion-dependent exocytosis and biological process this GO :0034220 and ion transmembrane transport and biological process this GO :0055085 and transmembrane transport and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070588 and calcium ion transmembrane transport and biological process, this GO :0005216: ion channel activity, this GO :0005216: ion channel activity and also this GO :0005262: calcium channel activity and also this GO :0005515: protein binding and also this GO :0005516: calmodulin binding, this GO :0005262: calcium channel activity, this GO :0005515: protein binding, this GO :0005516: calmodulin binding, transient receptor potential cation channel
Identity 14006
Gene TRPV6
Long gene name transient receptor potential cation channel subfamily V member 6
Synonyms gene ECAC2
Synonyms gene name epithelial calcium channel 2 transient receptor potential cation channel, member 6 , subfamily V
Synonyms CaT1
Locus 7q34
Discovery year 2000-11-24
GenBank acession AJ277909
Entrez gene record 55503
Pubmed identfication 11097838 11549322 16382100 16717058
RefSeq identity NM_014274
Classification Ankyrin repeat domain containing Transient receptor potential cation channels
Havana BLAST/BLAT OTTHUMG00000157158

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