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TSC1 (357CT4.4.2) Monoclonal Antibody

TSC1 (357CT4.4.2) Monoclonal Antibody size: 0.1ml 211

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 211
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name2) Monoclonal Antibody, 4, TSC1 (357CT4
Also known as2) Monoclonal Antibody, 4, TSC1 (357CT4
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenTSC1
SpecificityThis is a highly specific antibody against TSC1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number2, 357CT4, 4
SourcePurified His-tagged TSC1 protein(Fragment) was used to produced this monoclonal antibody
Gene ID number7248
Swiss ProtQ92574
Tested ApplicationsWB
Recommended dilutionsWB(1:100~250)
Cross reactivity Mouse, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Implicated as a tumor suppressor, Involved in microtubule-mediated protein transport, Seems not to be required for TSC2 GAP activity towards RHEB, but this seems to be due to unregulated mTOR signaling, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling, In complex with TSC2
Purification method This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Hamartin, KIAA0243, TSC, TSC1, Tuberous sclerosis 1 protein, LAM
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target2) Monoclonal, 4, TSC1 (357CT4
Short name2) Monoclonal Antibody, 4, TSC1 (357CT4
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name2) monoclonal (Antibody to), 4, TSC1 (357CT4
Alternative techniqueantibodies
Identity 12362
Gene TSC1
Long gene name tuberous sclerosis 1
Synonyms gene TSC
Synonyms KIAA0243 LAM hamartin
Locus 9q34
Discovery year 1986-01-01
GenBank acession AF013168
Pubmed identfication 9242607 10806479
Havana BLAST/BLAT OTTHUMG00000020844
Locus Specific Databases TSC Mutation Database Tuberous sclerosis database LRG_486

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