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TSC1 Antibody (phospho-S312)

TSC1 Antibody (phospho-S312) size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenTSC1 (phospho-S312)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus)
Tested applications ELISA, DB
Recommended dilutionsDot blot: 1:500
NotesTitration of the phospho-TSC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis phospho-TSC1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q9EP53
PurityAntigen affinity
Description Implicated as a tumor suppressor, Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity), inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity), In complex with TSC2
ImmunogenThis phospho-TSC1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS312 of mouse TSC1
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the phospho-TSC1 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetTSC1 (phospho-S312)
Short nameTSC1 Antibody (phospho-S312)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameTSC1 (Antibody to) (phosphorilated-S312)
Alternative techniqueantibodies
Identity 12362
Gene TSC1
Long gene name tuberous sclerosis 1
Synonyms gene TSC
Synonyms KIAA0243 LAM hamartin
Locus 9q34
Discovery year 1986-01-01
GenBank acession AF013168
Pubmed identfication 9242607 10806479
Havana BLAST/BLAT OTTHUMG00000020844
Locus Specific Databases TSC Mutation Database Tuberous sclerosis database LRG_486

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