Filters

TSC2 Antibody

TSC2 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenTSC2
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the TSC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis TSC2 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P49815
PurityAntigen affinity
Description Alternative splicing results in multiple transcript variants encoding different isoforms, Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases, The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin, Mutations in this gene lead to tuberous sclerosis complex
ImmunogenA portion of amino acids 479-508 from the human protein was used as the immunogen for this TSC2 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the TSC2 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetTSC2
Short nameTSC2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nametuberous sclerosis 2 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target 14-3-3 protein binding, LAM and PPP1R160 and TSC4, TSC2 and IDBG-635000 and ENSBTAG00000020617 and 504985, TSC2 and IDBG-9819 and ENSG00000103197 and 7249, Tsc2 and IDBG-147651 and ENSMUSG00000002496 and 22084, nuclei, this GO :0001666 and response to hypoxia and biological process this GO :0001843 and neural tube closure and biological process this GO :0005096 and GTPase activator activity and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005901 and caveola and cellular component this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0006606 and protein import into nucleus and biological process this GO :0006897 and endocytosis and biological process this GO :0006953 and acute-phase response and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007165 and signal transduction and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007507 and heart development and biological process this GO :0008104 and protein localization and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0014065 and phosphatidylinositol 3-kinase signaling and biological process this GO :0014067 and negative regulation of phosphatidylinositol 3-kinase signaling and biological process this GO :0016020 and membrane and cellular component this GO :0016192 and vesicle-mediated transport and biological process this GO :0019902 and phosphatase binding and molecular function this GO :0030030 and cell projection organization and biological process this GO :0030100 and regulation of endocytosis and biological process this GO :0030178 and negative regulation of Wnt signaling pathway and biological process this GO :0030425 and dendrite and cellular component this GO :0030426 and growth cone and cellular component this GO :0032007 and negative regulation of TOR signaling and biological process this GO :0032320 and positive regulation of Ras GTPase activity and biological process this GO :0033596 and TSC1-TSC2 complex and cellular component this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043005 and neuron projection and cellular component this GO :0043025 and neuronal cell body and cellular component this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043234 and protein complex and cellular component this GO :0043407 and negative regulation of MAP kinase activity and biological process this GO :0043491 and protein kinase B signaling and biological process this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045184 and establishment of protein localization and biological process this GO :0045792 and negative regulation of cell size and biological process this GO :0046626 and regulation of insulin receptor signaling pathway and biological process this GO :0046627 and negative regulation of insulin receptor signaling pathway and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048009 and insulin-like growth factor receptor signaling pathway and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :0050918 and positive chemotaxis and biological process this GO :0051056 and regulation of small GTPase mediated signal transduction and biological process this GO :0051260 and protein homooli this GO merization and biological process this GO :0051291 and protein heterooli this GO merization and biological process this GO :0051726 and regulation of cell cycle and biological process this GO :0051898 and negative regulation of protein kinase B signaling and biological process this GO :0071889 and 14-3-3 protein binding and molecular function, this GO :0005096: GTPase activator activity, this GO :0005096: GTPase activator activity and also this GO :0005488: binding and also this GO :0005515: protein binding and also this GO :0019902: phosphatase binding and also this GO :0042803: protein homodimerization activity and also this GO :0046982: protein heterodimerization activity and also this GO :0071889: 14-3-3 protein binding, this GO :0005488: binding, this GO :0005515: protein binding, this GO :0019902: phosphatase binding, this GO :0042803: protein homodimerization activity, this GO :0046982: protein heterodimerization activity, this GO :0071889: 14-3-3 protein binding, tuberous sclerosis 2
Identity 12363
Gene TSC2
Long gene name tuberous sclerosis 2
Synonyms gene TSC4
Synonyms tuberin LAM PPP1R160
Synonyms name protein phosphatase 1, regulatory subunit 160
Locus 16p13, 3
Discovery year 1989-05-25
GenBank acession AB014460
Entrez gene record 7249
Pubmed identfication 1303246 7558029
RefSeq identity NM_000548
Classification Protein phosphatase 1 regulatory subunits
Havana BLAST/BLAT OTTHUMG00000128745
Locus Specific Databases TSC2 Mutation Database Tuberous sclerosis database LRG_487

Similar products

Subscribe to our Newsletter