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TSEN2 Antibody

TSEN2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameTSEN2 Primary Polyclonal Antibody
Also known asTSEN2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenTSEN2
SpecificityThis is a highly specific antibody against TSEN2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TSEN2
Gene ID number80746
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Defects in the gene encoding TSEN2 are the cause of pontocerebellar hypoplasia type 2B, In addition to its role in pre-tRNA splicing, Isoform 1 seems to carry the active site for 5â, TSEN2 (tRNA-splicing endonuclease subunit Sen2), There are three isoforms of TSEN2 that are produced as a result of alternative splicing events, also known as tRNA-intron endonuclease Sen2, and 3â, extrapyramidal dyskinesia and chorea without spinal cord findings, is a 465 amino acid nuclear protein that constitutes one of the two catalytic subunits of the tRNA-splicing endonuclease complex, is thought to link pre-tRNA and pre-mRNA splicing events, splice sites, the heterotetrameric endonuclease complex participates in mRNA processing and, thereby releasing introns and free tRNA molecules with 2', via its association with pre-mRNA processing factors, which is characterized by progressive microencephaly with epilepsy, &euro, &euro, &euro, &trade, &trade, &trade, -splice site cleavage, 3' cyclic phosphates and 5'-OH termini, The tRNA-splicing endonuclease complex is responsible for identifying and cleaving pre-tRNA at both 5â
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names MGC2776, MGC4440, S, SEN2, SEN2L, SEN2_HUMAN, TSEN 2, cerevisiae, tRNA intron endonuclease Sen2, tRNA splicing endonuclease 2 homolog SEN2, tRNA splicing endonuclease subunit Sen2, HsSen2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetTSEN2
Short nameTSEN2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameTSEN2 (Antibody to)
Alternative techniqueantibodies
Identity 28422
Gene TSEN2
Long gene name tRNA splicing endonuclease subunit 2
Synonyms gene name S, cerevisiae) TSEN2 tRNA splicing endonuclease subunit , cerevisiae) tRNA splicing endonuclease 2 homolog (S, tRNA splicing endonuclease 2 homolog (SEN2
Synonyms SEN2 SEN2L MGC2776
Locus 3p25, 2
Discovery year 2005-03-07
GenBank acession BC019582
Entrez gene record 80746
Pubmed identfication 15109492
RefSeq identity NM_025265
Classification tRNA-splicing endonuclease subunits
Havana BLAST/BLAT OTTHUMG00000129765

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