Name : TSEN2 Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN8722997674
| Long name | ALEXA FLUOR 647 Conjugated, TSEN2 Polyclonal Antibody |
| Also known as | Anti-TSEN2 PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | TSEN2 |
| Specificity | This is a highly specific antibody against TSEN2 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TSEN2 |
| Gene ID Number | 80746 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Defects in the gene encoding TSEN2 are the cause of pontocerebellar hypoplasia type 2B, In addition to its role in pre-tRNA splicing, Isoform 1 seems to carry the active site for 5â, TSEN2 (tRNA-splicing endonuclease subunit Sen2), There are three isoforms of TSEN2 that are produced as a result of alternative splicing events, also known as tRNA-intron endonuclease Sen2, and 3â, extrapyramidal dyskinesia and chorea without spinal cord findings, is a 465 amino acid nuclear protein that constitutes one of the two catalytic subunits of the tRNA-splicing endonuclease complex, is thought to link pre-tRNA and pre-mRNA splicing events, splice sites, the heterotetrameric endonuclease complex participates in mRNA processing and, thereby releasing introns and free tRNA molecules with 2', via its association with pre-mRNA processing factors, which is characterized by progressive microencephaly with epilepsy, &euro, &euro, &euro, &trade, &trade, &trade, -splice site cleavage, 3' cyclic phosphates and 5'-OH termini, The tRNA-splicing endonuclease complex is responsible for identifying and cleaving pre-tRNA at both 5â |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | SEN2 SEN2L MGC2776 |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the TSEN2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | TSEN2 |
| Short name | TSEN2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, TSEN2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 28422 |
| Gene | TSEN2 |
| Long gene name | tRNA splicing endonuclease subunit 2 |
| Synonyms gene name | S, cerevisiae) TSEN2 tRNA splicing endonuclease subunit , cerevisiae) tRNA splicing endonuclease 2 homolog (S, tRNA splicing endonuclease 2 homolog (SEN2 |
| Locus | 3p25, 2 |
| Discovery year | 2005-03-07 |
| GenBank acession | BC019582 |
| Entrez gene record | 80746 |
| Pubmed identfication | 15109492 |
| RefSeq identity | NM_025265 |
| Classification | tRNA-splicing endonuclease subunits |
| Havana BLAST/BLAT | OTTHUMG00000129765 |