Name : TSEN2 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN4707329791
| Long name | Biotin Conjugated, TSEN2 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | TSEN2 |
| Specificity | This is a highly specific antibody against TSEN2 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human TSEN2 |
| Gene ID number | 80746 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Defects in the gene encoding TSEN2 are the cause of pontocerebellar hypoplasia type 2B, In addition to its role in pre-tRNA splicing, Isoform 1 seems to carry the active site for 5â, TSEN2 (tRNA-splicing endonuclease subunit Sen2), There are three isoforms of TSEN2 that are produced as a result of alternative splicing events, also known as tRNA-intron endonuclease Sen2, and 3â, extrapyramidal dyskinesia and chorea without spinal cord findings, is a 465 amino acid nuclear protein that constitutes one of the two catalytic subunits of the tRNA-splicing endonuclease complex, is thought to link pre-tRNA and pre-mRNA splicing events, splice sites, the heterotetrameric endonuclease complex participates in mRNA processing and, thereby releasing introns and free tRNA molecules with 2', via its association with pre-mRNA processing factors, which is characterized by progressive microencephaly with epilepsy, &euro, &euro, &euro, &trade, &trade, &trade, -splice site cleavage, 3' cyclic phosphates and 5'-OH termini, The tRNA-splicing endonuclease complex is responsible for identifying and cleaving pre-tRNA at both 5â |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | SEN2 SEN2L MGC2776 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | TSEN2 Conjugated |
| Short name | Conjugated, TSEN2 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, TSEN2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 28422 |
| Gene | TSEN2 |
| Long gene name | tRNA splicing endonuclease subunit 2 |
| Synonyms gene name | S, cerevisiae) TSEN2 tRNA splicing endonuclease subunit , cerevisiae) tRNA splicing endonuclease 2 homolog (S, tRNA splicing endonuclease 2 homolog (SEN2 |
| Locus | 3p25, 2 |
| Discovery year | 2005-03-07 |
| GenBank acession | BC019582 |
| Entrez gene record | 80746 |
| Pubmed identfication | 15109492 |
| RefSeq identity | NM_025265 |
| Classification | tRNA-splicing endonuclease subunits |
| Havana BLAST/BLAT | OTTHUMG00000129765 |