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TSEN2 Antibody, Biotin Conjugated

TSEN2 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, TSEN2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTSEN2
SpecificityThis is a highly specific antibody against TSEN2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human TSEN2
Gene ID number80746
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Defects in the gene encoding TSEN2 are the cause of pontocerebellar hypoplasia type 2B, In addition to its role in pre-tRNA splicing, Isoform 1 seems to carry the active site for 5â, TSEN2 (tRNA-splicing endonuclease subunit Sen2), There are three isoforms of TSEN2 that are produced as a result of alternative splicing events, also known as tRNA-intron endonuclease Sen2, and 3â, extrapyramidal dyskinesia and chorea without spinal cord findings, is a 465 amino acid nuclear protein that constitutes one of the two catalytic subunits of the tRNA-splicing endonuclease complex, is thought to link pre-tRNA and pre-mRNA splicing events, splice sites, the heterotetrameric endonuclease complex participates in mRNA processing and, thereby releasing introns and free tRNA molecules with 2', via its association with pre-mRNA processing factors, which is characterized by progressive microencephaly with epilepsy, &euro, &euro, &euro, &trade, &trade, &trade, -splice site cleavage, 3' cyclic phosphates and 5'-OH termini, The tRNA-splicing endonuclease complex is responsible for identifying and cleaving pre-tRNA at both 5â
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms SEN2 SEN2L MGC2776
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetTSEN2 Conjugated
Short name Conjugated, TSEN2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, TSEN2 (Antibody to)
Alternative techniqueantibodies
Identity 28422
Gene TSEN2
Long gene name tRNA splicing endonuclease subunit 2
Synonyms gene name S, cerevisiae) TSEN2 tRNA splicing endonuclease subunit , cerevisiae) tRNA splicing endonuclease 2 homolog (S, tRNA splicing endonuclease 2 homolog (SEN2
Locus 3p25, 2
Discovery year 2005-03-07
GenBank acession BC019582
Entrez gene record 80746
Pubmed identfication 15109492
RefSeq identity NM_025265
Classification tRNA-splicing endonuclease subunits
Havana BLAST/BLAT OTTHUMG00000129765

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