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TSLC1 Antibody

TSLC1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameTSLC1 Primary Polyclonal Antibody
Also known asTSLC1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenTSLC1
SpecificityThis is a highly specific antibody against TSLC1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range396-442/442
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TSLC1
Gene ID number23705
Swiss ProtQ9BY67
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly (By similarity), Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells, Also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca(2+)-independent manner, CADM1, In mast cells, Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo, May be involved in neuronal migration, May contribute to the less invasive phenotypes of lepidic growth tumor cells, May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa, and fasciculation on the axons of differentiating neurons, axon growth, is essential for development and survival of mast cells in vivo, may mediate attachment to and promote communication with nerves, pathfinding, together with MITF, Mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CADM1, Cell adhesion molecule 1, IGSF4, IGSF4A, Immunoglobulin superfamily member 4, NECL2, Necl-2, Nectin-like protein 2, RA175, ST17, SYNCAM, Spermatogenic immunoglobulin superfamily, Synaptic cell adhesion molecule, TSLC-1, TSLC1, Tumor suppressor in lung cancer 1, sTSLC-1, sgIGSF, synCAM1, BL2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetTSLC1
Short nameTSLC1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameTSLC1 (Antibody to)
Alternative techniqueantibodies
Identity 5951
Gene CADM1
Long gene name cell adhesion molecule 1
Synonyms gene TSLC1 IGSF4
Synonyms gene name member 4 , tumor suppressor in lung cancer 1 immunoglobulin superfamily
Synonyms NECL2 ST17 BL2 SYNCAM IGSF4A Necl-2 SYNCAM1 RA175
Synonyms name nectin-like 2
Locus 11q23, 3
Discovery year 1998-11-02
GenBank acession AB017563
Entrez gene record 23705
Pubmed identfication 10610705
RefSeq identity NM_014333
Classification C2-set domain containing Immunoglobulin like domain containing V-set domain containing
Havana BLAST/BLAT OTTHUMG00000168202

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