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TSPAN12 Antibody

TSPAN12 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameTSPAN12 Primary Polyclonal Antibody
Also known asTSPAN12 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenTSPAN12
SpecificityThis is a highly specific antibody against TSPAN12
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range34-50/305
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TSPAN12
Gene ID number23554
Swiss ProtO95859
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Activates ADAM10-dependent cleavage activity of amyloid precursor protein (APP), Activates MMP14/MT1-MMP-dependent cleavage activity, Acts as a regulator of membrane proteinases such as ADAM10 and MMP14/MT1-MMP, Acts in concert with norrin (NDP) to promote FZD4 multimerization and subsequent activation of FZD4, Plays a central role in retinal vascularization by regulating norrin (NDP) signal transduction, Suprisingly, it only activate the norrin (NDP)-dependent activation of FZD4, leading to promote accumulation of beta-catenin (CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1) (By similarity), while it does not activate the Wnt-dependent activation of FZD4, Regulator of cell surface receptor signal transduction
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names NET-2, NET2, TM4SF12, TSPAN12, Tetraspan NET-2, Tetraspanin-12, Transmembrane 4 superfamily member 12, Tspan-12, UNQ774/PRO1568, EVR5
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetTSPAN12
Short nameTSPAN12 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameTSPAN12 (Antibody to)
Alternative techniqueantibodies
Identity 21641
Gene TSPAN12
Long gene name tetraspanin 12
Synonyms gene TM4SF12
Synonyms gene name transmembrane 4 superfamily member 12
Synonyms NET-2
Locus 7q31, 31
Discovery year 2003-07-21
GenBank acession AF124522
Entrez gene record 23554
RefSeq identity NM_012338
Classification Tetraspanins
Havana BLAST/BLAT OTTHUMG00000156980

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