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TSPAN12 Antibody, Biotin Conjugated

TSPAN12 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, TSPAN12 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTSPAN12
SpecificityThis is a highly specific antibody against TSPAN12
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range34-50/305
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human TSPAN12
Gene ID number23554
Swiss ProtO95859
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Activates ADAM10-dependent cleavage activity of amyloid precursor protein (APP), Activates MMP14/MT1-MMP-dependent cleavage activity, Acts as a regulator of membrane proteinases such as ADAM10 and MMP14/MT1-MMP, Acts in concert with norrin (NDP) to promote FZD4 multimerization and subsequent activation of FZD4, Plays a central role in retinal vascularization by regulating norrin (NDP) signal transduction, Suprisingly, it only activate the norrin (NDP)-dependent activation of FZD4, leading to promote accumulation of beta-catenin (CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1) (By similarity), while it does not activate the Wnt-dependent activation of FZD4, Regulator of cell surface receptor signal transduction
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms NET-2
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetTSPAN12 Conjugated
Short name Conjugated, TSPAN12 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, TSPAN12 (Antibody to)
Alternative techniqueantibodies
Identity 21641
Gene TSPAN12
Long gene name tetraspanin 12
Synonyms gene TM4SF12
Synonyms gene name transmembrane 4 superfamily member 12
Locus 7q31, 31
Discovery year 2003-07-21
GenBank acession AF124522
Entrez gene record 23554
RefSeq identity NM_012338
Classification Tetraspanins
Havana BLAST/BLAT OTTHUMG00000156980

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