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TSPAN12 Antibody, FITC Conjugated

TSPAN12 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, TSPAN12 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTSPAN12
SpecificityThis is a highly specific antibody against TSPAN12
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range34-50/305
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human TSPAN12
Gene ID number23554
Swiss ProtO95859
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Activates ADAM10-dependent cleavage activity of amyloid precursor protein (APP), Activates MMP14/MT1-MMP-dependent cleavage activity, Acts as a regulator of membrane proteinases such as ADAM10 and MMP14/MT1-MMP, Acts in concert with norrin (NDP) to promote FZD4 multimerization and subsequent activation of FZD4, Plays a central role in retinal vascularization by regulating norrin (NDP) signal transduction, Suprisingly, it only activate the norrin (NDP)-dependent activation of FZD4, leading to promote accumulation of beta-catenin (CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1) (By similarity), while it does not activate the Wnt-dependent activation of FZD4, Regulator of cell surface receptor signal transduction
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms NET-2
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetTSPAN12 Conjugated
Short name FITC Conjugated, TSPAN12 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, TSPAN12 (Antibody to)
Alternative techniqueantibodies
Identity 21641
Gene TSPAN12
Long gene name tetraspanin 12
Synonyms gene TM4SF12
Synonyms gene name transmembrane 4 superfamily member 12
Locus 7q31, 31
Discovery year 2003-07-21
GenBank acession AF124522
Entrez gene record 23554
RefSeq identity NM_012338
Classification Tetraspanins
Havana BLAST/BLAT OTTHUMG00000156980

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