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TTBK2/SCA11 Antibody

TTBK2/SCA11 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameTTBK2/SCA11 Primary Polyclonal Antibody
Also known asTTBK2/SCA11 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenTTBK2/SCA11
SpecificityThis is a highly specific antibody against TTBK2/SCA11
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TTBK2/SCA11
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Defects in the SCA11 protein are the cause of the disorder spinocerebellar ataxia type 11 (SCA11), Existing as three alternatively spliced isoforms, It is a relatively benign, Patients show progressive incoordination of gait and often poor coordination of hands, Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders, The SCA11 disorder is an autosomal dominant cerebellar ataxia (ADCA), The SCA11 gene, The SCA11 protein has also been implicated in Alzheimer disease and in tangle formation, and maps to human chromosome 15q15, chicken and zebrafish, comprising of 16 exons, cow, dog, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord, late-onset, mouse, produces a 5, rat, slowly progressive neurologic disorder, speech and eye movements, the SCA11 gene is conserved in chimpanzee, 2, 244 amino acid protein that belongs to the protein kinase superfamily and the CK1 Ser/Thr protein kinase family, 6-kb transcript in which the longest open reading frame is 3, 732 nucleotides, SCA11 is a 1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names KIAA0847, SCA11, Spinocerebellar ataxia 11, TTBK, TTBK 2, TTBK1, TTBK2 , TTBK2_HUMAN, TTK, Tau tubulin kinase 2, Tau-tubulin kinase 2, mKIAA0847, TTBK2/SCA11 Tau tubulin kinase 2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetTTBK2/SCA11
Short nameTTBK2/SCA11 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameTTBK2/SCA11 (Antibody to)
Alternative techniqueantibodies
Identity 19141
Gene TTBK2
Long gene name tau tubulin kinase 2
Synonyms gene SCA11
Synonyms gene name spinocerebellar ataxia 11
Synonyms KIAA0847
Locus 15q15, 2
Discovery year 2003-05-28
GenBank acession AB020654
Entrez gene record 146057
Pubmed identfication 10048485
RefSeq identity NM_173500
Havana BLAST/BLAT OTTHUMG00000175802

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