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TUB 1 Antibody, ALEXA FLUOR 488

TUB 1 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, TUB 1 Polyclonal Antibody
Also known asAnti-TUB 1 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTUB 1
SpecificityThis is a highly specific antibody against TUB 1
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TUB 1
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen (5) and Bardet-Biedl (6), A Gè, A candidate for the tub gene has been described (4), A second prematurely truncated mRNA transcript with the unspliced intron was found to be expressed in the brains of tubby mice at a 2-3 fold higher rate as compared to B6 mice (4), In addition to excessive deposition of adipose tissue, It has been postulated that the phenotypic features of tubby mice can be attributed to cellular apoptosis triggered by the expression of a mutated tub gene (4), The tripartite character of tubby phenotype is strikingly similar to human obesity syndromes such as Alstré, mice with the tub phenotype also suffer retinal degeneration and neurosensory hearing loss (4-6), mutations in the tub gene lead to obesity gradually and strongly resemble late-onset obesity as seen in the human population (4), transversion in this candidate gene eliminates a donor splice site in the 3' coding region resulting in a larger transcript containing an unspliced intron (4), &Scaron, °, &ldquo, &permil, In contrast to the rapid early-onset weight gain seen in ob/ob mice (1-3)
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms rd5
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the TUB 1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetTUB 1
Short nameTUB 1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, tubby homolog (mouse) 1 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target TUB and IDBG-30462 and ENSG00000166402 and 7275, TUB and IDBG-633715 and ENSBTAG00000004862 and 539051, Tub and IDBG-206024 and ENSMUSG00000031028 and 22141, nuclei, protein complex binding, rd5, this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006909 and pha this GO cytosis and biological process this GO :0007602 and phototransduction and biological process this GO :0007605 and sensory perception of sound and biological process this GO :0008020 and G-protein coupled photoreceptor activity and molecular function this GO :0009584 and detection of visible light and biological process this GO :0009725 and response to hormone and biological process this GO :0032403 and protein complex binding and molecular function this GO :0044259 and multicellular organismal macromolecule metabolic process and biological process this GO :0050766 and positive regulation of pha this GO cytosis and biological process this GO :0060041 and retina development in camera-type eye and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0008020: G-protein coupled photoreceptor activity and also this GO :0032403: protein complex binding, this GO :0008020: G-protein coupled photoreceptor activity, this GO :0032403: protein complex binding, tubby homolog (mouse)
Identity 12406
Gene TUB
Long gene name tubby bipartite transcription factor
Synonyms gene name tubby (mouse) homolog tubby homolog (mouse)
Locus 11p15, 4
Discovery year 1996-10-11
GenBank acession U54644
Entrez gene record 7275
Pubmed identfication 8612280
RefSeq identity NM_003320
Havana BLAST/BLAT OTTHUMG00000165690

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