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TUG/ASPC Antibody

TUG/ASPC Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameTUG/ASPC Primary Polyclonal Antibody
Also known asTUG/ASPC PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenTUG/ASPC
SpecificityThis is a highly specific antibody against TUG/ASPC
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TUG/ASPC
Gene ID number79058
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Aberrant Glut4 expression has been suggested to contribute to such maladies as obesity and diabetes, Full-length TUG forms a complex with Glut4 and in 3T3-L1 adipocytes and this complex is present in unstimulated cells and is disassembled by insulin, Glut4 null mice have shown that while functional Glut4 protein is not required for maintaining normal glucose levels, Insulin mobilizes this pool of retained Glut4 by releasing the tether, TUG (ASPL in humans) regulates the trafficking of glucose via Glut4, TUG acts by trapping endocytosed Glut4 and tethering it intracellularly, fat metabolism and prolonged longevity, it is necessary for sustained growth, normal cellular glucose, Glut4 is a twelve pass transmembrane protein (12TM) whose carboxy-terminus may dictate its cellular localization
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ASPC, ASPC1_HUMAN, ASPCR 1, ASPCR1, ASPL, ASPS, ASPSCR 1, Alveolar soft part sarcoma chromosome region candidate 1 human, Alveolar soft part sarcoma locus, Aspscr1, FLJ45380, RCC 17, RCC17, Renal papillary cell carcinoma protein 17, TUG, Tether containing UBX domain for GLUT4, Tether containing a UBX domain for GLUT4, UBX domain containing protein 9, UBX domain protein 9, UBX domain-containing protein 9, UBXD 9, UBXD9, UBXN 9, UBXN9, renal cell carcinoma gene on chromosome 17, renal cell carcinoma papillary 17, Alveolar soft part sarcoma chromosomal region candidate gene 1 protein
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetTUG/ASPC
Short nameTUG/ASPC Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameTUG/ASPC (Antibody to)
Alternative techniqueantibodies
Identity 13825
Gene ASPSCR1
Long gene name ASPSCR1, UBX domain containing tether for SLC2A4
Synonyms gene name alveolar soft part sarcoma chromosome region, candidate 1
Synonyms ASPS ASPL UBXD9 UBXN9 TUG
Synonyms name UBX domain protein 9 Tether containing UBX domain for GLUT4
Locus 17q25, 3
Discovery year 2001-04-05
GenBank acession AF324219
Entrez gene record 79058
Pubmed identfication 11244503 10506710
RefSeq identity NM_024083
Classification UBX domain containing
Havana BLAST/BLAT OTTHUMG00000178438

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