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Twinkle/ATXN8 Antibody, Cy5 Conjugated

Twinkle/ATXN8 Antibody, Cy5 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5 Conjugated, Twinkle/ATXN8 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTwinkle/ATXN8
SpecificityThis is a highly specific antibody against Twinkle/ATXN8
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human Twinkle/ATXN8
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Colocalized with mtDNA (mitochondrial DNA) in mitochondrial nucleoids, Defects in the gene encoding Twinkle are the cause of two conditions: progressive external ophthalmoplegia with mitochondrial DNA deletions autosomal dominant 3 (PEOA3) and sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), PEOA3, PEOA3 is characterized by ptosis and weak muscles, SANDO or TWINL, Twinkle is expressed at high levels in testis, Twinkle is important in the metabolism and maintenance of mtDNA, also known as PEO1 (Progressive external ophthalmoplegia 1 protein), dysarthria and sensory ataxic neuropathies, is a mitochondrial protein that functions as a 5â, nucleotide-dependent DNA helicase, pancreas and skeletal muscle and exists as three isoforms due to alternative splicing events, playing a crucial role in the regulation of mtDNA copy numbers, while SANDO is characterized by ophthalmoparesis, &euro, &euro, &trade, &trade, -3â, Twinkle
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission625, 650nm/670nm
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetTwinkle/ATXN8 Conjugated
Short name Conjugated, Twinkle/ATXN8 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy5
Alternative name cyanine 5 coupled, Twinkle/ATXN8 (Antibody to)
Alternative techniqueantibodies
Identity 32925
Gene ATXN8
Long gene name ataxin 8
Locus 13q21, 33
Discovery year 2006-07-18
GenBank acession DQ641254
Entrez gene record 724066
Pubmed identfication 16804541
Classification Ataxins

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