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TWIST protein Antibody

TWIST protein Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameTWIST protein Primary Polyclonal Antibody
Also known asTWIST protein PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenTWIST
SpecificityThis is a highly specific antibody against TWIST
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range108-150/202
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TWIST
Gene ID number7291
Swiss ProtQ15672
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Activates transcription as a heterodimer with E proteins, Also represses expression of proinflammatory cytokines such as TNFA and IL1B, Heterodimerization is also required for osteoblast differentiation, Homodimers induce expression of FGFR2 and POSTN while heterodimers repress FGFR2 and POSTN expression and induce THBS1 expression, Inhibits myogenesis by sequestrating E proteins, Regulates cranial suture patterning and fusion, Regulates gene expression differentially, Represses the activity of the circadian transcriptional activator: NPAS2-ARNTL/BMAL1 heterodimer (By similarity), This interaction probably involves the basic domains of both proteins, and inhibiting DNA-binding by MYOD1 through physical interaction, depending on dimer composition, inhibiting trans-activation by MEF2, Acts as a transcriptional regulator
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ACS3, BPES2, BPES3, CRS1, Class A basic helix-loop-helix protein 38, H-twist, SCS, TWIST, TWIST1, Twist-related protein 1, bHLHa38, CRS
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetTWIST protein
Short nameTWIST protein Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameTWIST protein (Antibody to)
Alternative techniqueantibodies
Identity 12428
Gene TWIST1
Long gene name twist family bHLH transcription factor 1
Synonyms gene ACS3 BPES3 TWIST CRS
Synonyms gene name blepharophimosis, epicanthus inversus and ptosis 3 acrocephalosyndactyly 3 twist homolog 1 (Drosophila) twist basic helix-loop-helix transcription factor 1 craniosynostosis
Synonyms SCS H-twist BPES2 bHLHa38 CRS1
Synonyms name Saethre-Chotzen syndrome
Locus 7p21, 1
Discovery year 1997-07-01
GenBank acession U80998
Entrez gene record 7291
Pubmed identfication 8995765 11474656 17343269
RefSeq identity NM_000474
Classification Basic helix-loop-helix proteins
Havana BLAST/BLAT OTTHUMG00000090821

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