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TWIST protein Antibody, FITC Conjugated

TWIST protein Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, TWIST protein Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTWIST
SpecificityThis is a highly specific antibody against TWIST
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range108-150/202
Subcellular locationNucleus
SourceKLH conjugated synthetic peptide derived from human TWIST
Gene ID number7291
Swiss ProtQ15672
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Activates transcription as a heterodimer with E proteins, Also represses expression of proinflammatory cytokines such as TNFA and IL1B, Heterodimerization is also required for osteoblast differentiation, Homodimers induce expression of FGFR2 and POSTN while heterodimers repress FGFR2 and POSTN expression and induce THBS1 expression, Inhibits myogenesis by sequestrating E proteins, Regulates cranial suture patterning and fusion, Regulates gene expression differentially, Represses the activity of the circadian transcriptional activator: NPAS2-ARNTL/BMAL1 heterodimer (By similarity), This interaction probably involves the basic domains of both proteins, and inhibiting DNA-binding by MYOD1 through physical interaction, depending on dimer composition, inhibiting trans-activation by MEF2, Acts as a transcriptional regulator
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms SCS H-twist BPES2 bHLHa38 CRS1
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetTWIST protein Conjugated
Short name FITC Conjugated, TWIST protein Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, TWIST protein (Antibody to)
Alternative techniqueantibodies
Identity 12428
Gene TWIST1
Long gene name twist family bHLH transcription factor 1
Synonyms gene ACS3 BPES3 TWIST CRS
Synonyms gene name blepharophimosis, epicanthus inversus and ptosis 3 acrocephalosyndactyly 3 twist homolog 1 (Drosophila) twist basic helix-loop-helix transcription factor 1 craniosynostosis
Synonyms name Saethre-Chotzen syndrome
Locus 7p21, 1
Discovery year 1997-07-01
GenBank acession U80998
Entrez gene record 7291
Pubmed identfication 8995765 11474656 17343269
RefSeq identity NM_000474
Classification Basic helix-loop-helix proteins
Havana BLAST/BLAT OTTHUMG00000090821

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