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TXNIP Antibody

TXNIP Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameTXNIP Primary Polyclonal Antibody
Also known asTXNIP PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenTXNIP
SpecificityThis is a highly specific antibody against TXNIP
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range140-190/391
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TXNIP
Gene ID number10628
Swiss ProtQ9H3M7
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts as a suppressor of tumor cell growth, Functions as a transcriptional repressor, Inhibits the proteasomal degradation of DDIT4, Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, Required for the maturation of natural killer cells, and over-expression will induce G0/G1 cell cycle arrest, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1), blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names EST01027, HHCPA78, TXNIP, Thioredoxin-binding protein 2, Thioredoxin-interacting protein, VDUP1, Vitamin D3 up-regulated protein 1, THIF
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetTXNIP
Short nameTXNIP Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameTXNIP (Antibody to)
Alternative techniqueantibodies
Identity 16952
Gene TXNIP
Long gene name thioredoxin interacting protein
Synonyms VDUP1 EST01027 HHCPA78 THIF ARRDC6
Synonyms name upregulated by 1, 25-dihydroxyvitamin D-3 thioredoxin binding protein 2
Locus 1q21, 1
Discovery year 2001-12-12
GenBank acession S73591
Entrez gene record 10628
Pubmed identfication 8086474
RefSeq identity NM_006472
Classification Alpha arrestins
Havana BLAST/BLAT OTTHUMG00000013755

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