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Tyro3 (1444CT895.86.31) Monoclonal Antibody

Tyro3 (1444CT895.86.31) Monoclonal Antibody size: 0.1ml 211

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 211
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name31) Monoclonal Antibody, 86, Tyro3 (1444CT895
Also known as31) Monoclonal Antibody, 86, Tyro3 (1444CT895
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenTyro3
SpecificityThis is a highly specific antibody against Tyro3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number1444CT895, 31, 86
SourceThis Tyro3 antibody is generated from a mouse immunized with a recombinant protein
Gene ID number22174
Swiss ProtP55144
Tested ApplicationsWB
Recommended dilutionsWB(1:2000)
Cross reactivityMouse
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Activates the AKT survival pathway, Following activation by ligand, Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules, Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, Regulates many physiological processes including cell survival, TYRO3 signaling plays a role in various processes such as neuron protection from excitotoxic injury, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes, interacts with PIK3R1 and thereby enhances PI3-kinase activity, migration and differentiation, platelet aggregation and cytoskeleton reorganization, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3, Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names AI323366, Dtk, Etk-2, Rse, Sky, TK19-2, Tif, Tyro3, Tyrosine-protein kinase DTK, Tyrosine-protein kinase RSE, Tyrosine-protein kinase TIF, Tyrosine-protein kinase receptor TYRO3, etk2/tyro3, tk19-1, Brt
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target31) Monoclonal, 86, Tyro3 (1444CT895
Short name31) Monoclonal Antibody, 86, Tyro3 (1444CT895
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name31) monoclonal (Antibody to), 86, TYRO3 protein tyrosine kinase (1444CT895
Alternative techniqueantibodies

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