Name : UACA Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN6924105267
| Long name | UACA Primary Polyclonal Antibody |
| Also known as | UACA PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | UACA |
| Specificity | This is a highly specific antibody against UACA |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 330-380/1416 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human UACA |
| Gene ID number | 55075 |
| Swiss Prot | Q9BZF9 |
| Tested Applications | IF(ICC), IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(ICC)(1:50-200), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Bovine, Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity), Interaction with ARF6 may modulate cell shape and motility after injury (By similarity), LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation, Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility, Promotes apoptosis by regulating three pathways, Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress, apoptosome up-regulation, Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | KIAA1561, UACA, Uveal autoantigen with coiled-coil domains and ankyrin repeats, NUCLING |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | UACA |
| Short name | UACA Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | uveal autoantigen with coiled-coil domains and ankyrin repeats (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BT, UACA and IDBG-19585 and ENSG00000137831 and 55075, Uaca and IDBG-173915 and ENSMUSG00000034485 and 72565, nuclei, protein binding, this GO :0003674 and molecular function and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005634 and nucleus and cellular component this GO :0005635 and nuclear envelope and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0008150 and biological process and biological process this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0008631 and intrinsic apoptotic signaling pathway in response to oxidative stress and biological process this GO :0009411 and response to UV and biological process this GO :0016020 and membrane and cellular component this GO :0042307 and positive regulation of protein import into nucleus and biological process this GO :0042347 and negative regulation of NF-kappaB import into nucleus and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043293 and apoptosome and cellular component this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0003674: molecular_function, this GO :0003674: molecular_function and also this GO :0005515: protein binding, this GO :0005515: protein binding, 26227 and IDBG-645550 and ENSBTAG00000013982 and 281559, uveal autoantigen with coiled-coil domains and ankyrin repeats |
| Identity | 15947 |
| Gene | UACA |
| Long gene name | uveal autoantigen with coiled-coil domains and ankyrin repeats |
| Synonyms | FLJ10128 KIAA1561 |
| Synonyms name | nucling |
| Locus | 15q23 |
| Discovery year | 2001-06-29 |
| GenBank acession | AF322916 |
| Entrez gene record | 55075 |
| Pubmed identfication | 11162650 10997877 |
| Classification | Ankyrin repeat domain containing |
| Havana BLAST/BLAT | OTTHUMG00000133363 |