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UBE2O Antibody

UBE2O Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameUBE2O Primary Polyclonal Antibody
Also known asUBE2O PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenUBE2O
SpecificityThis is a highly specific antibody against UBE2O
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human UBE2O/E2 230K
Gene ID number63893
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Rat, Mouse
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen BRCA1 is directly involved in DNA repair, Expressed predominately in heart and skeletal muscle, Like p53, Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome, The gene encoding UBE2O maps to human chromosome 17, Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death, Two key tumor suppressor genes are associated with chromosome 17, UBE2O functions to catalyze the ATP-dependent covalent attachment of ubiquitin to select proteins, also known as E2-230K, colon, is a 1, namely, p53 and BRCA1, prostate gland and fallopian tubes, thereby targeting the ubiquitinated proteins for proteasomal degradation, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, which comprises over 2, 200 genes, 292 amino acid member of the uniquitin-conjugating enzyme family that is involved in protein modification, 5% of the human genome and encodes over 1, UBE20
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names EC=6, FLJ12878, KIAA1734, Likely Ortholog of Mouse Ubiquitin Conjugating Enzyme, RP23 193A16, UBE2O, UBE2O_HUMAN, Ubiquitin carrier protein O, Ubiquitin conjugating enzyme E2 O, ubiquitin conjugating enzyme E2O, ubiquitin-conjugating enzyme E2O, 2, 3, 5, 19, E2 230K
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetUBE2O
Short nameUBE2O Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameUBE2O (Antibody to)
Alternative techniqueantibodies
Identity 29554
Gene UBE2O
Long gene name ubiquitin conjugating enzyme E2 O
Synonyms gene name ubiquitin-conjugating enzyme E2O
Synonyms E2-230K
Locus 17q25, 1
Discovery year 2005-12-15
GenBank acession AB051521
Entrez gene record 63893
Pubmed identfication 11311559 11214970
RefSeq identity NM_022066
Havana BLAST/BLAT OTTHUMG00000180178

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