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Ubiquitin+1 (40B3) Monoclonal Antibody

Ubiquitin+1 (40B3) Monoclonal Antibody size: 0.1ml 362

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 362
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameUbiquitin+1 (40B3) Monoclonal Antibody
Also known asUbiquitin+1 (40B3) Monoclonal Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenUbiquitin +1
SpecificityThis is a highly specific antibody against Ubiquitin +1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number40B3
SourceSynthetic peptide (KLH coupled) corresponding to C-terminal residues of human Ubiquitin +1
Gene ID number7311
Swiss ProtP62987
Tested Applications IP, WB
Recommended dilutionsWB (1:500-1000) IP (1-2 ul )
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen 60S ribosomal protein L40: Component of the 60S subunit of the ribosome, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B, Linear polymer chains formed via attachment by the initiator Met lead to cell signaling, Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation, Lys-29-linked is involved in lysosomal degradation, Lys-33-linked is involved in kinase modification, Lys-48-linked is involved in protein degradation via the proteasome, Lys-63-linked is involved in endocytosis, Polyubiquitin chains, Ribosomal protein L40 is essential for translation of a subset of cellular transcripts, Ubiquitin is usually conjugated to Lys residues of target proteins, When covalently bound, When polyubiquitin is free (unanchored-polyubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains), and especially for cap-dependent translation of vesicular stomatitis virus mRNAs, and in signaling, conjugation to Cys or Ser residues has been observed, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair, however, in rare cases, it also has distinct roles, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), or free (unanchored), such as in activation of protein kinases, when attached to a target protein, Ubiquitin: Exists either covalently attached to another protein
Purification methodAmmonium sulfate precipitation
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CEP52, HUBCEP52, RPL40, UBA52, UBCEP2, Ubiquitin A-52 residue ribosomal protein fusion product 1, Ubiquitin-60S ribosomal protein L40, L40
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene targetUbiquitin+1 (40B3) Monoclonal
Short nameUbiquitin+1 (40B3) Monoclonal Antibody
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative nameUbiquitin+1 (40B3) monoclonal (Antibody to)
Alternative techniqueantibodies

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