| Long name | Ubiquitin Primary Polyclonal Antibody |
| Also known as | Ubiquitin PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Ubiquitin |
| Specificity | This is a highly specific antibody against Ubiquitin |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 5-55/685 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Ubiquitin |
| Gene ID number | 7316 |
| Swiss Prot | P0CG48 |
| Tested Applications | IF(ICC), IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(ICC)(1:50-200), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Pig, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B, Linear polymer chains formed via attachment by the initiator Met lead to cell signaling, Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation, Lys-29-linked is involved in lysosomal degradation, Lys-33-linked is involved in kinase modification, Lys-48-linked is involved in protein degradation via the proteasome, Lys-63-linked is involved in endocytosis, Polyubiquitin chains, Ubiquitin is usually conjugated to Lys residues of target proteins, When covalently bound, When polyubiquitin is free (unanchored-polyubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains), and in signaling, conjugation to Cys or Ser residues has been observed, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair, however, in rare cases, it also has distinct roles, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), or free (unanchored), such as in activation of protein kinases, when attached to a target protein, Ubiquitin: Exists either covalently attached to another protein |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Polyubiquitin-C, UBC, HMG2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Ubiquitin |
| Short name | Ubiquitin Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Ubiquitin (Antibody to) |
| Alternative technique | antibodies |
| Identity | 12621 |
| Gene | USP22 |
| Long gene name | ubiquitin specific peptidase 22 |
| Synonyms gene | USP3L |
| Synonyms gene name | ubiquitin specific protease 22 ubiquitin specific peptidase 3-like |
| Synonyms | KIAA1063 |
| Locus | 17p11, 2 |
| Discovery year | 1999-12-20 |
| GenBank acession | AB028986 |
| Entrez gene record | 23326 |
| Pubmed identfication | 12838346 |
| Classification | Ubiquitin specific peptidases SAGA complex |
| Havana BLAST/BLAT | OTTHUMG00000133621 |
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