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Ubiquitin Antibody, ALEXA FLUOR 350

Ubiquitin Antibody, ALEXA FLUOR 350 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 350 Conjugated, Ubiquitin Polyclonal Antibody
Also known asAnti-Ubiquitin PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenUbiquitin
SpecificityThis is a highly specific antibody against Ubiquitin
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range5-55/685
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Ubiquitin
Gene ID Number7316
Swiss ProtP0CG48
Tested applications IF(ICC), IF(IHC-P)
Recommended dilutions IF(ICC)(1:50-200), IF(IHC-P)(1:50-200)
Crossreactivity Mouse, Pig, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B, Linear polymer chains formed via attachment by the initiator Met lead to cell signaling, Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation, Lys-29-linked is involved in lysosomal degradation, Lys-33-linked is involved in kinase modification, Lys-48-linked is involved in protein degradation via the proteasome, Lys-63-linked is involved in endocytosis, Polyubiquitin chains, Ubiquitin is usually conjugated to Lys residues of target proteins, When covalently bound, When polyubiquitin is free (unanchored-polyubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains), and in signaling, conjugation to Cys or Ser residues has been observed, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair, however, in rare cases, it also has distinct roles, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), or free (unanchored), such as in activation of protein kinases, when attached to a target protein, Ubiquitin: Exists either covalently attached to another protein
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Synonyms KIAA1063
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetUbiquitin
Short nameUbiquitin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, Ubiquitin (Antibody to)
Alternative techniqueantibodies
Identity 12621
Gene USP22
Long gene name ubiquitin specific peptidase 22
Synonyms gene USP3L
Synonyms gene name ubiquitin specific protease 22 ubiquitin specific peptidase 3-like
Locus 17p11, 2
Discovery year 1999-12-20
GenBank acession AB028986
Entrez gene record 23326
Pubmed identfication 12838346
Classification Ubiquitin specific peptidases SAGA complex
Havana BLAST/BLAT OTTHUMG00000133621

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