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Ubiquitin D Antibody, ALEXA FLUOR 594

Ubiquitin D Antibody, ALEXA FLUOR 594 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 594 Conjugated, Ubiquitin D Polyclonal Antibody
Also known asAnti-Ubiquitin D PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenUbiquitin D
SpecificityThis is a highly specific antibody against Ubiquitin D
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range60-100/165
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Ubiquitin D
Gene ID Number10537
Swiss ProtO15205
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Conjugation ability activated by UBA6, May be involved in dendritic cell (DC) maturation, May be involved in the formation of aggresomes when proteasome is saturated or impaired, Mediates apoptosis in a caspase-dependent manner, Mediates mitotic non-disjunction and chromosome instability, Probably functions as a survival factor, Promotes the expression of the proteasome subunit beta type-9 (PSMB9/LMP2), Regulates TNF-alpha-induced and LPS-mediated activation of the central mediator of innate immunity NF-kappa-B by promoting TNF-alpha-mediated proteasomal degradation of ubiquitinated-I-kappa-B-alpha, Required for TNF-alpha-induced p65 nuclear translocation in renal tubular epithelial cells (RTECs), by abbreviating mitotic phase and impairing the kinetochore localization of MAD2L1 during the prometaphase stage of the cell cycle, especially in renal epithelium and tubular cells during renal diseases such as polycystic kidney disease and Human immunodeficiency virus (HIV)-associated nephropathy (HIVAN), in a NUB1L-dependent manner, in long-term in vitro culture and cancers, the process by which immature dendritic cells differentiate into fully competent antigen-presenting cells that initiate T-cell responses, Ubiquitin-like protein modifier which can be covalently attached to target protein and subsequently leads to their degradation by the 26S proteasome
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms FAT10
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetUbiquitin D
Short nameUbiquitin D Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, Ubiquitin D (Antibody to)
Alternative techniqueantibodies
Identity 18795
Gene UBD
Long gene name ubiquitin D
Locus 6p22, 1
Discovery year 2002-06-19
GenBank acession Y12653
Entrez gene record 10537
Pubmed identfication 9368598 8662070
Havana BLAST/BLAT OTTHUMG00000031289

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