Name : UBR2 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN6213024095
| Long name | FITC Conjugated, UBR2 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | UBR2 |
| Specificity | This is a highly specific antibody against UBR2 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human UBR2 |
| Gene ID number | 23304 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Mice lacking Ubr2 are infertile due to defects in male meiosis, Participating in protein modification events within the N-end rule pathway, The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), Ubr2 (Ubiquitin-protein ligase E3-alpha-2), Ubr2 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, also known as N-recognin-2, is a 1755 amino acid protein that contains one UBR-type zinc finger and one RING-type zinc finger, the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s), thereby leading to their ubiquitination and subsequent degradation, Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | bA49A4, 1 dJ392M17, 3 KIAA0349 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | UBR2 Conjugated |
| Short name | FITC Conjugated, UBR2 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, UBR2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 21289 |
| Gene | UBR2 |
| Long gene name | ubiquitin protein ligase E3 component n-recognin 2 |
| Synonyms gene | C6orf133 |
| Synonyms gene name | chromosome 6 open reading frame 133 |
| Locus | 6p21, 1 |
| Discovery year | 2003-11-26 |
| GenBank acession | BC024217 |
| Entrez gene record | 23304 |
| RefSeq identity | NM_015255 |
| Classification | Ubiquitin protein ligase E3 component n-recognins |
| Havana BLAST/BLAT | OTTHUMG00000014703 |