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UBR2 Antibody, FITC Conjugated

UBR2 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, UBR2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenUBR2
SpecificityThis is a highly specific antibody against UBR2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human UBR2
Gene ID number23304
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Mice lacking Ubr2 are infertile due to defects in male meiosis, Participating in protein modification events within the N-end rule pathway, The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), Ubr2 (Ubiquitin-protein ligase E3-alpha-2), Ubr2 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, also known as N-recognin-2, is a 1755 amino acid protein that contains one UBR-type zinc finger and one RING-type zinc finger, the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s), thereby leading to their ubiquitination and subsequent degradation, Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms bA49A4, 1 dJ392M17, 3 KIAA0349
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetUBR2 Conjugated
Short name FITC Conjugated, UBR2 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, UBR2 (Antibody to)
Alternative techniqueantibodies
Identity 21289
Gene UBR2
Long gene name ubiquitin protein ligase E3 component n-recognin 2
Synonyms gene C6orf133
Synonyms gene name chromosome 6 open reading frame 133
Locus 6p21, 1
Discovery year 2003-11-26
GenBank acession BC024217
Entrez gene record 23304
RefSeq identity NM_015255
Classification Ubiquitin protein ligase E3 component n-recognins
Havana BLAST/BLAT OTTHUMG00000014703

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