Name : UCHL1+3 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN9130982571
| Long name | UCHL1+3 Primary Polyclonal Antibody |
| Also known as | UCHL1+3 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | UCHL1+3 |
| Specificity | This is a highly specific antibody against UCHL1+3 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human UCHL1+3 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | The activity of UCHL3 is more than 200 fold higher than UCHL1 when a fluorogenic ubiquitin substrate is used, UCHL1 and UCHL3, UCHL1 and UCHL3 are both small proteins of ~220 amino acids that share more than 40% amino acid sequence identity, UCHL1 and UCHL3 play a role in the regulation of neuronal development and spermatogenesis, UCHL1 associates with monoubiquitin and UCHL3 binds to Nedd8, UCHL1 is involved in the pathogenesis of Parkinsonâ, UCHL3 is universally expressed in all tissues, deubiquitinate ubiquitin-protein conjugates and control the cellular balance of ubiquitin, testis and ovary, ubiquitin-like protein, while UCHL1 is expressed exclusively in neuronal tissue, &euro, &euro, &trade, &trade, The two ubiquitin C-terminal hydrolase (UCH) enzymes, s disease (AD), s disease (PD) and Alzheimerâ |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | UCHL1, UCHL3, Ubiquitin carboxyl terminal esterase L1, Ubiquitin carboxyl terminal esterase L3, Ubiquitin carboxyl terminal hydrolase isozyme L1, Ubiquitin carboxyl terminal hydrolase isozyme L3, Ubiquitin thiolesterase, Ubiquitin C terminal esterase L1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | UCHL1+3 |
| Short name | UCHL1+3 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | UCHL1+3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 12513 |
| Gene | UCHL1 |
| Long gene name | ubiquitin C-terminal hydrolase L1 |
| Synonyms gene | PARK5 |
| Synonyms gene name | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| Synonyms | PGP9, 5 Uch-L1 |
| Synonyms name | ubiquitin thiolesterase |
| Locus | 4p13 |
| Discovery year | 1991-07-15 |
| GenBank acession | BC000332 |
| Entrez gene record | 7345 |
| Pubmed identfication | 1840236 |
| RefSeq identity | NM_004181 |
| Classification | Ubiquitin C-terminal hydrolases Parkinson disease associated genes |
| Havana BLAST/BLAT | OTTHUMG00000099377 |