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UCHL1+3 Antibody, Biotin Conjugated

UCHL1+3 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, UCHL1+3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenUCHL1+3
SpecificityThis is a highly specific antibody against UCHL1+3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human UCHL1+3
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background The activity of UCHL3 is more than 200 fold higher than UCHL1 when a fluorogenic ubiquitin substrate is used, UCHL1 and UCHL3, UCHL1 and UCHL3 are both small proteins of ~220 amino acids that share more than 40% amino acid sequence identity, UCHL1 and UCHL3 play a role in the regulation of neuronal development and spermatogenesis, UCHL1 associates with monoubiquitin and UCHL3 binds to Nedd8, UCHL1 is involved in the pathogenesis of Parkinsonâ, UCHL3 is universally expressed in all tissues, deubiquitinate ubiquitin-protein conjugates and control the cellular balance of ubiquitin, testis and ovary, ubiquitin-like protein, while UCHL1 is expressed exclusively in neuronal tissue, &euro, &euro, &trade, &trade, The two ubiquitin C-terminal hydrolase (UCH) enzymes, s disease (AD), s disease (PD) and Alzheimerâ
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms PGP9, 5 Uch-L1
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetUCHL1+3 Conjugated
Short name Conjugated, UCHL1+3 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, UCHL1+3 (Antibody to)
Alternative techniqueantibodies
Identity 12513
Gene UCHL1
Long gene name ubiquitin C-terminal hydrolase L1
Synonyms gene PARK5
Synonyms gene name ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
Synonyms name ubiquitin thiolesterase
Locus 4p13
Discovery year 1991-07-15
GenBank acession BC000332
Entrez gene record 7345
Pubmed identfication 1840236
RefSeq identity NM_004181
Classification Ubiquitin C-terminal hydrolases Parkinson disease associated genes
Havana BLAST/BLAT OTTHUMG00000099377

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