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UCHL3 Antibody

UCHL3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameUCHL3 Primary Polyclonal Antibody
Also known asUCHL3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenUCHL3
SpecificityThis is a highly specific antibody against UCHL3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range130-180/230
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human UCHL3
Gene ID number7347
Swiss ProtP15374
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Examination of specific brain regions reveals expression in all areas tested, Expression of UCH-L1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors, Its occurrence in Lewy bodies and its function in the proteasome pathway make it a compelling candidate gene in Parkinson disease, The 230 amino acid human UCH-L3 protein is 54% identical to that of UCH-L1, The gene which encodes UCH-L1 maps to human chromosome 4p14, UCH-L1 is expressed in brain neurons, UCH-L1 represents 1 to 2% of total soluble brain protein, UCH-L3 is the predominant thiol protease and has high-affinity binding sites for ubiquitin, particularly in the substantia nigra, UCH-L1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names UCH L3, UCH-L3, UCHL3, UCHL3_HUMAN, Ubiquitin thioesterase L3, Ubiquitin thiolesterase, Ubiquitin thiolesterase L3, Ubiquitin carboxyl-terminal hydrolase isozyme L3
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetUCHL3
Short nameUCHL3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameUCHL3 (Antibody to)
Alternative techniqueantibodies
Identity 12515
Gene UCHL3
Long gene name ubiquitin C-terminal hydrolase L3
Synonyms gene name ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
Synonyms name ubiquitin thiolesterase
Locus 13q22, 2
Discovery year 1991-07-15
GenBank acession M30496
Entrez gene record 7347
Pubmed identfication 2530630
RefSeq identity NM_006002
Classification Ubiquitin C-terminal hydrolases
Havana BLAST/BLAT OTTHUMG00000017090

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