Name : UCHL3 Antibody, ALEXA FLUOR 350
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN2049042332
| Long name | ALEXA FLUOR 350 Conjugated, UCHL3 Polyclonal Antibody |
| Also known as | Anti-UCHL3 PAb ALEXA FLUOR 350 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 350, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | UCHL3 |
| Specificity | This is a highly specific antibody against UCHL3 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 130-180/230 |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human UCHL3 |
| Gene ID Number | 7347 |
| Swiss Prot | P15374 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Examination of specific brain regions reveals expression in all areas tested, Expression of UCH-L1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors, Its occurrence in Lewy bodies and its function in the proteasome pathway make it a compelling candidate gene in Parkinson disease, The 230 amino acid human UCH-L3 protein is 54% identical to that of UCH-L1, The gene which encodes UCH-L1 maps to human chromosome 4p14, UCH-L1 is expressed in brain neurons, UCH-L1 represents 1 to 2% of total soluble brain protein, UCH-L3 is the predominant thiol protease and has high-affinity binding sites for ubiquitin, particularly in the substantia nigra, UCH-L1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 343nm/442nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 350, Alexa Fluor |
| Gene target | UCHL3 |
| Short name | UCHL3 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 350 |
| Alternative name | ALEXA FLUOR 350, UCHL3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 12515 |
| Gene | UCHL3 |
| Long gene name | ubiquitin C-terminal hydrolase L3 |
| Synonyms gene name | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) |
| Synonyms name | ubiquitin thiolesterase |
| Locus | 13q22, 2 |
| Discovery year | 1991-07-15 |
| GenBank acession | M30496 |
| Entrez gene record | 7347 |
| Pubmed identfication | 2530630 |
| RefSeq identity | NM_006002 |
| Classification | Ubiquitin C-terminal hydrolases |
| Havana BLAST/BLAT | OTTHUMG00000017090 |