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UCHL3 Antibody, Biotin Conjugated

UCHL3 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, UCHL3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenUCHL3
SpecificityThis is a highly specific antibody against UCHL3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range130-180/230
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from human UCHL3
Gene ID number7347
Swiss ProtP15374
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Examination of specific brain regions reveals expression in all areas tested, Expression of UCH-L1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors, Its occurrence in Lewy bodies and its function in the proteasome pathway make it a compelling candidate gene in Parkinson disease, The 230 amino acid human UCH-L3 protein is 54% identical to that of UCH-L1, The gene which encodes UCH-L1 maps to human chromosome 4p14, UCH-L1 is expressed in brain neurons, UCH-L1 represents 1 to 2% of total soluble brain protein, UCH-L3 is the predominant thiol protease and has high-affinity binding sites for ubiquitin, particularly in the substantia nigra, UCH-L1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetUCHL3 Conjugated
Short name Conjugated, UCHL3 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, UCHL3 (Antibody to)
Alternative techniqueantibodies
Identity 12515
Gene UCHL3
Long gene name ubiquitin C-terminal hydrolase L3
Synonyms gene name ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
Synonyms name ubiquitin thiolesterase
Locus 13q22, 2
Discovery year 1991-07-15
GenBank acession M30496
Entrez gene record 7347
Pubmed identfication 2530630
RefSeq identity NM_006002
Classification Ubiquitin C-terminal hydrolases
Havana BLAST/BLAT OTTHUMG00000017090

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