Name : UFD1L Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN6984709200
| Long name | FITC Conjugated, UFD1L Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | UFD1L |
| Specificity | This is a highly specific antibody against UFD1L |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human UFD1L |
| Gene ID number | 7353 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | The NPLOC4-UFD1L-VCP complex also regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope, This complex, UFD1L gene hemizygosity is the cause of some developmental defects including DiGeorge syndrome (DGS), UFD1L has 2 named isoforms produced by alternative splicing, VCP and NPLOC4, also containing UFD1L, binds ubiquitinated proteins and is required for the export of misfolded proteins from the ER to the cytoplasm for disposal, velo-cardio-facial syndrome (VCFS) and Opitz G/BBB syndrome, UFD1L is a member of the UFD1 family of proteins and is a component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | UFD1 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | UFD1L Conjugated |
| Short name | FITC Conjugated, UFD1L Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, UFD1L (Antibody to) |
| Alternative technique | antibodies |
| Identity | 12520 |
| Gene | UFD1L |
| Long gene name | ubiquitin fusion degradation 1 like (yeast) |
| Synonyms gene name | ubiquitin fusion degradation 1-like |
| Locus | 22q11, 21 |
| Discovery year | 1997-05-09 |
| GenBank acession | AJ239058 |
| Entrez gene record | 7353 |
| Pubmed identfication | 9063746 |
| Havana BLAST/BLAT | OTTHUMG00000150130 |