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UHRF1/2 Antibody

UHRF1/2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameUHRF1/2 Primary Polyclonal Antibody
Also known asUHRF1/2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenUHRF1/2
SpecificityThis is a highly specific antibody against UHRF1/2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range720-770/793
Subcellular locationHelical
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human UHRF1
Gene ID number29128, 115426
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Also ubiquitinates PCNP leading to its degradation by the proteasome, Binds to inverted 5'-CCAAT-3' box 2 in the TOP2A promoter, CCND1 and CCNE1, E3 SUMO-, Important for G1/S transition, May be involved in DNA repair and chromosomal stability, May participate in methylation-dependent transcriptional regulation, Overexpressed in breast cancer, Through cooperative DNA and histone binding, UHRF2 is an E3 ubiquitin-protein ligase that is an intermolecular hub protein in the cell cycle network, Ubiquitinates cyclins, and activates TOP2A expression, bone marrow, but not ubiquitin-, in an apparently phosphorylation-independent manner and induces G1 arrest, lung and heart, may contribute to a tighter epigenetic control of gene expression in differentiated cells, protein ligase for ZNF131, testis, Putative E3 ubiquitin-protein ligase, Tissue specificity:Expressed in thymus
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 1, 90-kD, 95-KD, E3 ubiquitin-protein ligase UHRF1, E3 ubiquitin-protein ligase UHRF2, ICBP90, Inverted CCAAT box binding protein, Inverted CCAAT box binding protein of 90 kDa, Inverted CCAAT box-binding protein of 90 kDa, Liver regeneration-related protein LRRG126, NP95, Nuclear phosphoprotein, Nuclear protein 95, Nuclear zinc finger protein Np95, RING finger protein 106, RNF106, Transcription factor ICBP90, UHRF1, UHRF1_HUMAN, UHRF2, UHRF2_HUMAN, Ubiquitin like PHD and RING finger domain containing protein 1, Ubiquitin like containing PHD and RING finger domains protein 1, Ubiquitin-like, Ubiquitin-like PHD and RING finger domain-containing protein 1, Ubiquitin-like protein containing PHD and RING finger domains 1, Ubiquitin-like with PHD and ring finger domains 1, Ubiquitin-like-containing PHD and RING finger domains protein 1, Ubiquitin-like-containing PHD and RING finger domains protein 2, containing PHD and RING finger domains, HuNp95
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetUHRF1/2
Short nameUHRF1/2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameUHRF1/2 (Antibody to)
Alternative techniqueantibodies
Identity 12556
Gene UHRF1
Long gene name ubiquitin like with PHD and ring finger domains 1
Synonyms ICBP90 Np95 FLJ21925 RNF106 TDRD22
Locus 19p13, 3
Discovery year 2000-03-15
GenBank acession AF129507
Entrez gene record 29128
Pubmed identfication 10646863
RefSeq identity NM_001048201
Classification PHD finger proteins Ring finger proteins Tudor domain containing
Havana BLAST/BLAT OTTHUMG00000180251

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