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UHRF1/2 Antibody, Cy7 Conjugated

UHRF1/2 Antibody, Cy7 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, UHRF1/2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenUHRF1/2
SpecificityThis is a highly specific antibody against UHRF1/2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range720-770/793
Subcellular locationHelical
SourceKLH conjugated synthetic peptide derived from human UHRF1
Gene ID number29128, 115426
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Also ubiquitinates PCNP leading to its degradation by the proteasome, Binds to inverted 5'-CCAAT-3' box 2 in the TOP2A promoter, CCND1 and CCNE1, E3 SUMO-, Important for G1/S transition, May be involved in DNA repair and chromosomal stability, May participate in methylation-dependent transcriptional regulation, Overexpressed in breast cancer, Through cooperative DNA and histone binding, UHRF2 is an E3 ubiquitin-protein ligase that is an intermolecular hub protein in the cell cycle network, Ubiquitinates cyclins, and activates TOP2A expression, bone marrow, but not ubiquitin-, in an apparently phosphorylation-independent manner and induces G1 arrest, lung and heart, may contribute to a tighter epigenetic control of gene expression in differentiated cells, protein ligase for ZNF131, testis, Putative E3 ubiquitin-protein ligase, Tissue specificity:Expressed in thymus
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms ICBP90 Np95 FLJ21925 RNF106 TDRD22
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetUHRF1/2 Conjugated
Short name Conjugated, UHRF1/2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, UHRF1/2 (Antibody to)
Alternative techniqueantibodies
Identity 12556
Gene UHRF1
Long gene name ubiquitin like with PHD and ring finger domains 1
Locus 19p13, 3
Discovery year 2000-03-15
GenBank acession AF129507
Entrez gene record 29128
Pubmed identfication 10646863
RefSeq identity NM_001048201
Classification PHD finger proteins Ring finger proteins Tudor domain containing
Havana BLAST/BLAT OTTHUMG00000180251

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