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UHRF1 Antibody

UHRF1 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenUHRF1
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IF, WB, FACS
Recommended dilutionsFlow Cytometry: 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
NotesTitration of the UHRF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis UHRF1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q96T88
PurityAntigen affinity
Description It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle, The protein binds to specific DNA sequences, and functions in the p53-dependent DNA damage checkpoint, and recruits a histone acetylase to regulate gene expression, UHRF1 is a member of a subfamily of RING-finger type E3 ubiquitin ligases
ImmunogenA portion of amino acids 229-257 from the human protein was used as the immunogen for this UHRF1 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the UHRF1 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetUHRF1
Short nameUHRF1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameUHRF1 (Antibody to)
Alternative techniqueantibodies
Identity 12556
Gene UHRF1
Long gene name ubiquitin like with PHD and ring finger domains 1
Synonyms ICBP90 Np95 FLJ21925 RNF106 TDRD22
Locus 19p13, 3
Discovery year 2000-03-15
GenBank acession AF129507
Entrez gene record 29128
Pubmed identfication 10646863
RefSeq identity NM_001048201
Classification PHD finger proteins Ring finger proteins Tudor domain containing
Havana BLAST/BLAT OTTHUMG00000180251

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