Name : UHRF1 Antibody
Supplier : NJS POLY
Price :199
SKU : GEN4166690125
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | UHRF1 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, IF, WB, FACS |
| Recommended dilutions | Flow Cytometry: 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes | Titration of the UHRF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This UHRF1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q96T88 |
| Purity | Antigen affinity |
| Description | It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle, The protein binds to specific DNA sequences, and functions in the p53-dependent DNA damage checkpoint, and recruits a histone acetylase to regulate gene expression, UHRF1 is a member of a subfamily of RING-finger type E3 ubiquitin ligases |
| Immunogen | A portion of amino acids 229-257 from the human protein was used as the immunogen for this UHRF1 antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the UHRF1 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | UHRF1 |
| Short name | UHRF1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | UHRF1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 12556 |
| Gene | UHRF1 |
| Long gene name | ubiquitin like with PHD and ring finger domains 1 |
| Synonyms | ICBP90 Np95 FLJ21925 RNF106 TDRD22 |
| Locus | 19p13, 3 |
| Discovery year | 2000-03-15 |
| GenBank acession | AF129507 |
| Entrez gene record | 29128 |
| Pubmed identfication | 10646863 |
| RefSeq identity | NM_001048201 |
| Classification | PHD finger proteins Ring finger proteins Tudor domain containing |
| Havana BLAST/BLAT | OTTHUMG00000180251 |