ULK2 (218CT21.2.6) Monoclonal Antibody

ULK2 (218CT21.2.6) Monoclonal Antibody size: 0.1ml 211

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 211

Size 0.1ml

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Long name	2, 6) Monoclonal Antibody, ULK2 (218CT21
Also known as	2, 6) Monoclonal Antibody, ULK2 (218CT21
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	ULK2
Specificity	This is a highly specific antibody against ULK2
Modification(s)	None
Modification site(s)	Unmodified antibody
Clonality	Monoclonal
Clone number	2, 218CT21, 6
Source	This ULK2 monoclonal antibody is generated from mouse immunized with ULK2 recombinant protein
Gene ID number	9706
Swiss Prot	Q8IYT8
Tested Applications	WB
Recommended dilutions	WB(1:100)
Cross reactivity	Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	Activated via phosphorylation by AMPK, Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, FRS2, FRS3 and RPTOR, May phosphorylate ATG13/KIAA0652, Not involved in ammonia-induced autophagy or in autophagic response of cerebellar granule neurons (CGN) to low potassium concentration, PRKAB2 and PRKAG1, Part of regulatory feedback loops in autophagy: acts both as a downstream effector and a negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR, Plays a role early in neuronal differentiation and is required for granule cell axon formation: may govern axon formation via Ras-like GTPase signaling and through regulation of the Rab5-mediated endocytic pathways within developing axons, also acts as a negative regulator of AMPK through phosphorylation of the AMPK subunits PRKAA1, however such data need additional evidences, the precursors of autophagosomes, Serine/threonine-protein kinase involved in autophagy in response to starvation
Purification method	This antibody is prepared by Euglobin precipitation followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	KIAA0623, Serine/threonine-protein kinase ULK2, ULK2, Unc-51-like kinase 2, Unc51, 2, ATG1B
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About	Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target	2, 6) Monoclonal, ULK2 (218CT21
Short name	2, 6) Monoclonal Antibody, ULK2 (218CT21
Technique	Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name	2, 6) monoclonal (Antibody to), ULK2 (218CT21
Alternative technique	antibodies
Identity	13480
Gene	ULK2
Long gene name	unc-51 like autophagy activating kinase 2
Synonyms gene name	elegans) , elegans)-like kinase 2 unc-51-like kinase 2 (C, unc-51 (C
Synonyms	KIAA0623 Unc51, 2 ATG1B
Locus	17p11, 2
Discovery year	2001-11-23
GenBank acession	AB014523
Entrez gene record	9706
Pubmed identfication	10557072
RefSeq identity	NM_014683
Classification	Autophagy related
Havana BLAST/BLAT	OTTHUMG00000059511

ULK2 (218CT21.2.6) Monoclonal Antibody

ULK2 (218CT21.2.6) Monoclonal Antibody size: 0.1ml 211

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