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ULK3 (1404CT148.89.25) Monoclonal Antibody

ULK3 (1404CT148.89.25) Monoclonal Antibody size: 0.1ml 211

Price 211
Size 0.1ml
Long name25) Monoclonal Antibody, 89, ULK3 (1404CT148
Also known as25) Monoclonal Antibody, 89, ULK3 (1404CT148
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenULK3
SpecificityThis is a highly specific antibody against ULK3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number1404CT148, 25, 89
SourceThis ULK3 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 435-468 amino acids from the C-terminal region of human ULK3
Gene ID number25989
Swiss ProtQ6PHR2
Tested ApplicationsWB
Recommended dilutionsWB( 1:1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, Also acts as a regulator of autophagy: following cellular senescence, GLI2 and/or GLI3), Phosphorylates in vitro GLI2, Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, able to induce autophagy, activating it and promoting its nuclear translocation, although less efficiently, as well as GLI1 and GLI3, autophosphorylates and mediates phosphorylation of GLI2, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy
Purification method This antibody is purified through a protein G column, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ULK3, Unc-51-like kinase 3, Serine/threonine-protein kinase ULK3
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target25) Monoclonal, 89, ULK3 (1404CT148
Short name25) Monoclonal Antibody, 89, ULK3 (1404CT148
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name25) monoclonal (Antibody to), 89, ULK3 (1404CT148
Alternative techniqueantibodies
Identity 19703
Gene ULK3
Long gene name unc-51 like kinase 3
Synonyms gene name elegans) , unc-51-like kinase 3 (C
Synonyms DKFZP434C131 FLJ90566
Locus 15q24, 1
Discovery year 2005-01-19
GenBank acession BC048289
Entrez gene record 25989
RefSeq identity NM_015518
Havana BLAST/BLAT OTTHUMG00000173020

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