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Unc5a/UNC5H1 Antibody, ALEXA FLUOR 555

Unc5a/UNC5H1 Antibody, ALEXA FLUOR 555 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 555 Conjugated, Unc5a/UNC5H1 Polyclonal Antibody
Also known asAnti-Unc5a/UNC5H1 PAb ALEXA FLUOR 555
CategoryConjugated Primary Antibodies
Conjugated with 555, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenUnc5a/UNC5H1
SpecificityThis is a highly specific antibody against Unc5a/UNC5H1
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Unc5a
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Additionally, In the absence of netrin-1, The expression of UNC5H receptors is downregulated in multiple carcinomas, This activity is blocked by the binding of netrin-1, Three isoforms of UNC5H1 exist due to alternative splicing events, UNC5H receptors act as tumor suppressors by inhibiting anchorage-independent growth and invasion, UNC5H1, also known as UNC5HA (unc-5 homolog A), breast, but mutation of these receptors provides a potential mechanism for tumorigenicity, including colorectal, is a member of the UNC5H family of proteins and is localized to the cell membrane, lung and kidney cancers, ovary, stomach, uterus, when cleaved by a caspase to produce an intracellular fragment containing a death domain, The UNC5H family of proteins act as transmembrane receptors for netrin-1 and play a crucial role in axon guidance and migration of neural cells, UNC5H receptors induce apoptosis
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission553nm/568nm
Synonyms KIAA1976 UNC5H1
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 555, Alexa Fluor
Gene targetUnc5a/UNC5H1
Short nameUnc5a/UNC5H1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 555
Alternative name ALEXA FLUOR 555, elegans)/UNC5H1 (Antibody to), unc-5 homolog A (C
Alternative techniqueantibodies
Identity 12567
Gene UNC5A
Long gene name unc-5 netrin receptor A
Synonyms gene name elegans) , unc5 (C, elegans homolog) a unc-5 homolog A (C
Locus 5q35, 2
Discovery year 1998-12-09
GenBank acession AB075856
Entrez gene record 90249
Pubmed identfication 12655055 20372800
RefSeq identity XM_030300
Classification I-set domain containing
Havana BLAST/BLAT OTTHUMG00000163225

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